Brosh K, Strassman I, Seelenfreund M
Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel.
Eye (Lond). 2014 Jul;28(7):892-4. doi: 10.1038/eye.2014.83. Epub 2014 May 2.
It is well known that altitude ascent with intravitreal gas can cause expansion of gas and intraocular pressure (IOP) elevation. According to Boyle's law, the gas bubble will not expand unless a higher altitude than the gas insertion site has been reached. We report four cases in which intravitreal gas was injected at an altitude of 790 m (Jerusalem). All four cases developed high IOP even though they did not reach a higher altitude in their post-operative period.
A report of four patients following vitrectomy with 12% mixture of perfluoropropane and air are presented. All four patients arrived with ocular pain following the ascent by car of 765-1100 m to Jerusalem where the vitrectomy and gas insertion was conducted. Upon examination, all four patients had high IOP (30-55 mm Hg). IOP was well controlled with IOP-lowering medications. None of the patients suffered from long-term complications.
Caution should be taken with altitude changes in patients with intravitreal gas even if there was no ascent from the altitude in which the vitrectomy was performed.
众所周知，眼内注入气体后海拔上升可导致气体膨胀和眼压（IOP）升高。根据玻意耳定律，除非到达高于气体注入部位的海拔高度，气泡不会膨胀。我们报告了4例在海拔790米（耶路撒冷）注入眼内气体的病例。尽管这4例患者术后未到达更高海拔，但均出现了高眼压。
报告了4例接受12%全氟丙烷和空气混合物玻璃体切割术的患者。所有4例患者乘车上升765 - 1100米至耶路撒冷后出现眼痛，在耶路撒冷进行了玻璃体切割术并注入气体。检查时，所有4例患者眼压均高（30 - 55毫米汞柱）。使用降眼压药物后眼压得到良好控制。所有患者均未出现长期并发症。
即使玻璃体腔内注入气体的患者未从进行玻璃体切割术的海拔高度上升，也应注意海拔变化。
