Semeraro Francesco, Morescalchi Francesco, Russo Andrea, Romano Mario R, Costagliola Ciro
Eye Clinic, Department of Neurological and Vision Sciences, University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy.
Eye Clinic, Istituto Clinico Humanitas, Via Manzoni 56, 20089 Milano, Italy.
Biomed Res Int. 2014;2014:618382. doi: 10.1155/2014/618382. Epub 2014 Jul 2.
Myopia is the most common ocular abnormality. Its high and growing prevalence has contributed to a recent surge in surgical interest in the disorder, since retinal detachment in eyes with high myopia differs from that in emmetropic eyes or eyes with low myopia. The myopic eye, because of its specific anatomy, poses special challenges that need to be overcome to ensure the appropriate use of vitreous substitutes. However, intraocular tamponades have shown great potential for revolutionizing retinal detachment surgery and vitreomacular surgery in general in myopic eyes. We provide an updated review of the clinical use of vitreous substitutes in the myopic eye, paying particular attention to analyzing the ideal function of endotamponade agents and comparing the effects of these agents on the physical and biological properties of the eye.
近视是最常见的眼部异常。其高患病率且不断上升,导致近期对该疾病的手术关注度激增,因为高度近视眼中的视网膜脱离与正视眼或低度近视眼中的视网膜脱离不同。由于其特殊的解剖结构,近视眼带来了特殊挑战,要确保玻璃体替代物的恰当使用就需要克服这些挑战。然而,眼内填塞物总体上已显示出在近视眼视网膜脱离手术和玻璃体黄斑手术中引发变革的巨大潜力。我们提供了近视眼玻璃体替代物临床应用的最新综述,特别关注分析内填塞剂的理想功能,并比较这些药物对眼的物理和生物学特性的影响。