Zhang X, Tian X, Hu Y, Zhang C, Wei C, Yang X
Department of Oral &Maxillofacial, Head & Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong, University School of Medicine, Shanghai 200011, China,
Med Oral Patol Oral Cir Bucal. 2018 May 1;23(3):e277-e281. doi: 10.4317/medoral.22225.
Peripheral ameloblastoma (PA) is a rare and unusual variant of odontogenic tumor, which was described only in isolated case reports in literature. The objective of this study was to investigate the clinical profile, treatment and outcome of PA in a consecutive case series.
A total of 25 patients with histologically confirmed PA from 2001 to 2015 were retrospectively reviewed in our institution.
Of the 25 patients, 22 males and 3 females were identified (male: female = 7.3:1). The average age was 48.3 years (range 11-81 years) with lingual or palate gingival region being the most common site (76%). The course of disease was less than 6 months in 92.0% (23/25) of all patients (mean, 3.3 months; range, 1-12 months). All patients underwent complete surgical removal of the lesions, and one lesion recurrence occurred during the follow-up period.
The clinical profile and outcome of PA from Eastern China were elucidated in this retrospective analysis based on a case series. Our experience may provide some insights into the differential diagnosis and clinical management of PA. The first choice of treatment is surgical excision, which can result in a good prognosis.
外周型成釉细胞瘤（PA）是一种罕见且特殊的牙源性肿瘤变体，文献中仅有孤立病例报道。本研究的目的是在一个连续病例系列中调查PA的临床特征、治疗方法及预后。
对我院2001年至2015年间25例经组织学确诊为PA的患者进行回顾性研究。
25例患者中，男性22例，女性3例（男∶女 = 7.3∶1）。平均年龄48.3岁（范围11 - 81岁），舌侧或腭侧牙龈区域是最常见的部位（76%）。92.0%（23/25）的患者病程小于6个月（平均3.3个月；范围1 - 12个月）。所有患者均接受了病变的完整手术切除，随访期间有1例病变复发。
本回顾性病例系列分析阐明了中国东部地区PA的临床特征及预后。我们的经验可能为PA的鉴别诊断和临床管理提供一些见解。治疗的首选方法是手术切除，可获得良好预后。
