Rizvi Saliha, Raza Syed T, Ahmed Faizal, Ahmad Absar, Abbas Shania, Mahdi Farzana
Department of Biochemistry, ERA'S Lucknow Medical College India, Lucknow, India.
Sultan Qaboos Univ Med J. 2014 May;14(2):e157-65. Epub 2014 Apr 7.
Vitamin E is the major lipid-soluble component in the cell antioxidant defence system and is exclusively obtained from the diet. It has numerous important roles within the body because of its antioxidant activity. Oxidation has been linked to numerous possible conditions and diseases, including cancer, ageing, arthritis and cataracts; vitamin E has been shown to be effective against these. Platelet hyperaggregation, which can lead to atherosclerosis, may also be prevented by vitamin E; additionally, it also helps to reduce the production of prostaglandins such as thromboxane, which cause platelet clumping. The current literature review discusses the functions and roles of vitamin E in human health and some diseases as well as the consequences of vitamin E deficiency. The main focus of the review is on the tocopherol class of the vitamers.
维生素E是细胞抗氧化防御系统中的主要脂溶性成分，且完全从饮食中获取。由于其抗氧化活性，它在体内具有许多重要作用。氧化与多种可能的病症和疾病有关，包括癌症、衰老、关节炎和白内障；已证明维生素E对这些病症有效。可能导致动脉粥样硬化的血小板过度聚集也可能被维生素E预防；此外，它还有助于减少诸如血栓素等导致血小板聚集的前列腺素的产生。当前的文献综述讨论了维生素E在人类健康和一些疾病中的功能与作用以及维生素E缺乏的后果。该综述的主要重点是维生素E的生育酚类别。
