Gharaee Hamid, Abrishami Mojtaba, Shafiee Masoud, Ehsaei Asieh
Cornea Research Center, Mashhad University of Medical Sciences, Mashhad 9195965919, Iran ; Eye Research Center, Mashhad University of Medical Sciences, Mashhad 9195965919, Iran.
Eye Research Center, Mashhad University of Medical Sciences, Mashhad 9195965919, Iran ; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, Iran.
Int J Ophthalmol. 2014 Apr 18;7(2):309-12. doi: 10.3980/j.issn.2222-3959.2014.02.20. eCollection 2014.
To determine the normative values of white-to-white corneal diameter with Orbscan II Topography System and to compare right and left eyes data in the normal young population.
A total of 1001 healthy participants aged 18-45y participated in this observational cross-sectional study. The study population consisted of 616 female and 385 male subjects. The corneal diameter was measured with the Orbscan II. The differences between genders, between right and left eyes and age-related changes were evaluated. Statistical analyses were performed using Student's t-test.
The average white-to-white distance in our study population was recorded as 11.65±0.36 mm (median: 11.60 mm, mode: 11.70 mm, minimum: 10.50 mm and maximum: 13.60 mm). The white-to-white distance was 11.60±0.35 mm in males and 11.71±0.36 mm in females which was statistically different between genders (P<0.01). However, white-to-white distance was not statistically different between right and left eyes. In addition, this parameter decreased with increasing age. Considering 95% confidence interval, corneal diameter less than 10.93 mm and greater than 12.34 mm would be considered as microcornea and megalocornea, respectively based on this study population, using the Orbscan II topography.
Detailed description and analysis of corneal diameter with Orbscan demonstrate that the obtained average value of horizontal white-to-white is higher in male than female and decreases slightly with increasing age. Our data also suggests the cut off values for definition of microcornea and megalocornea, which can be employed with this population.
采用Orbscan II角膜地形图系统测定角膜白对白直径的正常参考值,并比较正常年轻人群左右眼的数据。
1001名年龄在18至45岁的健康参与者参加了这项观察性横断面研究。研究人群包括616名女性和385名男性受试者。使用Orbscan II测量角膜直径。评估性别之间、左右眼之间的差异以及与年龄相关的变化。采用Student's t检验进行统计分析。
在我们的研究人群中,白对白平均距离记录为11.65±0.36mm(中位数:11.60mm,众数:11.70mm,最小值:10.50mm,最大值:13.60mm)。男性白对白距离为11.60±0.35mm,女性为11.71±0.36mm,性别之间存在统计学差异(P<0.01)。然而,左右眼之间的白对白距离无统计学差异。此外,该参数随年龄增长而降低。考虑到95%置信区间,基于本研究人群,使用Orbscan II地形图,角膜直径小于10.93mm和大于12.34mm分别被视为小角膜和大角膜。
使用Orbscan对角膜直径进行详细描述和分析表明,获得的水平白对白平均值男性高于女性,并随年龄增长略有下降。我们的数据还提出了小角膜和大角膜定义的临界值,可用于该人群。