Chen Yao, Xia Xiaobo
Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
BMC Ophthalmol. 2016 Mar 31;16:33. doi: 10.1186/s12886-016-0210-8.
The purpose of this study was to compare corneal power and horizontal corneal diameter (white-to-white [WTW] distance) readings obtained by the Orbscan II topographer and the iTrace aberrometer.
Keratometry readings in the flat (Kf) and steep (Ks) meridians and WTW distance were measured with the Orbscan II and iTrace systems in 100 myopic patients. Statistical evaluation was performed using the paired t test, Pearson correlation, and Bland-Altman analysis for comparison of measurement techniques.
The mean keratometry values with the Orbscan II and iTrace were 43.16 ± 1.44 and 42.64 ± 1.43 diopter (D), respectively (P < 0.0001). The mean WTW distance measurements with the Orbscan II and iTrace were 11.57 ± 0.34 and 11.33 ± 0.36 mm, respectively (P < 0.0001). For the measurement of corneal power, the 95 % limits of agreement (LoA) between the Orbscan II and iTrace were - 0.21 to 1.21 D for the flat meridian and - 0.15 to 1.25 D for the steep meridian. For the measurement of WTW distance, the range of the 95 % LoA between the two devices was 0.47 mm.
For some clinical applications, the keratometry and WTW distance measurements obtained by the Orbscan II topographer and the iTrace aberrometer differed greatly and therefore were not interchangeable.
Clinical trials number: ChiCTR-OCS-14005077 (August 2nd, 2014).
本研究旨在比较Orbscan II角膜地形图仪和iTrace像差仪所测得的角膜屈光力和角膜水平直径(白对白[WTW]距离)读数。
使用Orbscan II和iTrace系统对100例近视患者的角膜平坦(Kf)和陡峭(Ks)子午线的角膜曲率读数及WTW距离进行测量。采用配对t检验、Pearson相关性分析和Bland-Altman分析对测量技术进行统计学评估以作比较。
Orbscan II和iTrace所测得的平均角膜曲率值分别为43.16±1.44和42.64±1.43屈光度(D)(P<0.0001)。Orbscan II和iTrace所测得的平均WTW距离分别为11.57±0.34和11.33±0.36mm(P<0.0001)。对于角膜屈光力的测量,Orbscan II和iTrace之间在平坦子午线的95%一致性界限(LoA)为-0.21至1.21D,在陡峭子午线为-0.15至1.25D。对于WTW距离的测量,两种设备之间95% LoA的范围为0.47mm。
对于某些临床应用,Orbscan II角膜地形图仪和iTrace像差仪所测得的角膜曲率和WTW距离测量结果差异很大,因此不可互换。
临床试验编号:ChiCTR-OCS-14005077(2014年8月2日)。