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长期暴露于高强度职业噪音环境下的退休工人的心血管疾病死亡率。

Cardiovascular disease mortality among retired workers chronically exposed to intense occupational noise.

作者信息

Girard Serge Andre, Leroux Tony, Verreault René, Courteau Marilène, Picard Michel, Turcotte Fernand, Baril Julie, Richer Olivier

机构信息

Institut national de santé publique du Québec, Québec, Canada,

出版信息

Int Arch Occup Environ Health. 2015 Jan;88(1):123-30. doi: 10.1007/s00420-014-0943-8. Epub 2014 May 3.

Abstract

OBJECTIVE

The aim of this study, conducted among retired workers (≥65 years), is to estimate the association between long-term risk of cardiovascular disease (CVD) death and (1) duration of occupational noise exposure in career and (2) noise-induced hearing loss (NIHL), the latter being used as an indicator of adverse effects for long-term exposure to occupational noise.

METHODS

Data from screening activities of occupational NIHL were paired to data from death records and were used for this study. A nested case-control analysis was performed. Each case was matched with three controls for length of follow-up and economic sector. A total of 161 CVD deaths occured during an average follow-up of 6.8 years. Conditional logistic regression models were used to estimate the risk (OR) of CVD death by tertiles of duration of noise exposure and of NIHL.

RESULTS

Conditional logistic regression models indicated that prolonged duration of noise exposure (≥36.5 years) (3rd tertile) was associated with an increased risk of CVD death (OR 1.70; 95 % CI 1.10-2.62), as compared with shorter duration (<27 years) (first tertile). Moderate NIHL (2nd tertile) (OR 1.64; 95 % CI 1.04-2.6) and severe NIHL (3rd tertile) (OR 1.66; 95 % CI 1.06-2.60) were also associated with an increase in risk of CVD death.

CONCLUSIONS

Results are consistent with recent findings on the chronic effects of occupational noise exposure persisting after retirement although it is less than during active working life.

摘要

目的

本研究针对退休工人(≥65岁)开展,旨在评估心血管疾病(CVD)死亡的长期风险与以下因素之间的关联:(1)职业噪声暴露的职业生涯时长;(2)噪声性听力损失(NIHL),后者用作长期暴露于职业噪声产生的不良影响的指标。

方法

职业性NIHL筛查活动的数据与死亡记录的数据进行配对,并用于本研究。进行了巢式病例对照分析。每个病例与三个对照在随访时长和经济部门方面进行匹配。在平均6.8年的随访期间,共发生了161例CVD死亡。使用条件逻辑回归模型,通过噪声暴露时长和NIHL的三分位数来估计CVD死亡风险(OR)。

结果

条件逻辑回归模型表明,与较短时长(<27年)(第一三分位数)相比,延长的噪声暴露时长(≥36.5年)(第三三分位数)与CVD死亡风险增加相关(OR 1.70;95% CI 1.10 - 2.62)。中度NIHL(第二三分位数)(OR 1.64;95% CI 1.04 - 2.6)和重度NIHL(第三三分位数)(OR 1.66;95% CI 1.06 - 2.60)也与CVD死亡风险增加相关。

结论

研究结果与近期关于职业噪声暴露的慢性影响在退休后依然存在的发现一致,尽管其影响程度低于在职工作期间。

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