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HIV通过昆虫传播的可能性:半翅目臭虫和amboinensis巨蚊对人类免疫缺陷病毒的实验性暴露

Potential for insect transmission of HIV: experimental exposure of Cimex hemipterus and Toxorhynchites amboinensis to human immunodeficiency virus.

作者信息

Webb P A, Happ C M, Maupin G O, Johnson B J, Ou C Y, Monath T P

机构信息

Division of Vector-Borne Viral Diseases, Centers for Disease Control, Fort Collins, Colorado 80522.

出版信息

J Infect Dis. 1989 Dec;160(6):970-7. doi: 10.1093/infdis/160.6.970.

DOI:10.1093/infdis/160.6.970
PMID:2479697
Abstract

Human immunodeficiency virus (HIV) was detected in bedbugs (Cimex hemipterus) up to 8 d after oral exposure to highly concentrated virus in blood meals, but no virus replication was observed. HIV did not replicate in either intraabdominally inoculated bedbugs or intrathoracically inoculated mosquitoes (Toxorhynchites amboinensis). The virus was not detected in bedbug feces. Mechanical transmission of HIV by bedbugs could not be demonstrated in an in vitro model. The persistence of HIV in an insect or on its mouthparts is one of many factors necessary for mechanical transmission in nature. The risk of insect transmission of HIV appears to be extremely low or nonexistent.

摘要

在臭虫(热带臭虫)经口摄入高浓度含病毒血餐长达8天后检测到人类免疫缺陷病毒(HIV),但未观察到病毒复制。HIV在经腹腔接种的臭虫或经胸腔接种的蚊子(华丽巨蚊)中均未复制。在臭虫粪便中未检测到该病毒。在体外模型中无法证实臭虫对HIV的机械传播。HIV在昆虫体内或其口器上的持续存在是自然界中机械传播所需的众多因素之一。昆虫传播HIV的风险似乎极低或不存在。

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