Krannig Kai-Steffen, Schlaad Helmut
Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, Research Campus Golm, 14424 Potsdam, Germany.
Soft Matter. 2014 Jun 28;10(24):4228-35. doi: 10.1039/c4sm00352g.
This article highlights the very recent advances in glycopolypeptide synthesis via NCA polymerization and first studies on stimuli-responsive solution behavior and self-assembling structures. Yet glycopolypeptides are almost exclusively considered as smart biofunctional materials for use in biomedical applications, for instance in targeted drug delivery, but also have high potential for usage as structural materials to fabricate bioinspired hierarchical structures.
本文重点介绍了通过NCA聚合合成糖多肽的最新进展,以及对刺激响应溶液行为和自组装结构的首次研究。然而,糖多肽几乎完全被视为用于生物医学应用(例如靶向药物递送)的智能生物功能材料,但作为制造受生物启发的层次结构的结构材料也具有很高的潜力。