伊朗德黑兰皮肤赘生物患者与正常人群血脂水平的比较研究。

A comparison study of lipid profile levels between skin tags affected people and normal population in Tehran, Iran.

作者信息

Rasi Abbas, Faghihi Alireza, Rahmanzadeh Yaser, Hassannejad Habib

机构信息

Skin and Stem Cell Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran, Department of Dermatology, Rasoul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran, Department of Dermatology, Rasoul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Adv Biomed Res. 2014 Mar 31;3:109. doi: 10.4103/2277-9175.129709. eCollection 2014.

DOI:10.4103/2277-9175.129709

PMID:24804183

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4009752/

Abstract

BACKGROUND

For many years the association of skin tags and endocrynopathies has been postulated, although many reports are available but it has never been evaluated to mean normal population. Dyslipidemia is a frequent disorder among people and seemed to be necessary for screening within skin tag condition. This study is designed to find any possible association between skin tags and dyslipidemia.

MATERIALS AND METHODS

From April 2009 to June 2011, 168 patients enrolled the study. Among the remaining 152 patients, there were 89 females (58.5%) and 63 males (%41.5). Based on the TLGS study 136 men and 220 women enrolled the control group of study. The mean age was 28.4 years. Patients trained to have normal free diet for at least 1 month then referred to the laboratory. Blood samples were taken over 12 hours fasting with 2 hours intervals. Hypertriglyceridemia was defined as plasma level ≥160 mg/dl for men and ≥130 mg/dl for women. Hypercholesterolemia pointed at its value >200 mg/dl. Normal HDL levels was defined as >39 mg/dl for men and >35 mg/dl to women.

RESULTS

Mean skin tag number was 12.6 per subject. The most frequent localizations of skin tags were neck and upper chest (mean number: 13.4, 48.9%) followed by axilla (mean number: 11.6, 33%) and breast (10.2, 10.1%) in the patient group. The mean cholesterol level of case group was 192.2 ± 33.1 mg/dl, while it was 187.0 ± 42 mg/dl in the control group). The mean ± SD for triglyceride was 132.1 ± 69 mg/dl in comparison to 129 ± 74 in the control group.

CONCLUSION

The study showed no significant differences between normal population and patients' lipid profile.

摘要

背景

多年来一直推测皮赘与内分泌病有关，尽管有许多相关报道，但从未针对普通人群进行过评估。血脂异常在人群中是一种常见疾病，在皮赘患者中似乎有必要进行筛查。本研究旨在发现皮赘与血脂异常之间的任何可能关联。

材料与方法

2009年4月至2011年6月，168例患者纳入研究。在其余152例患者中，女性89例（58.5%），男性63例（41.5%）。基于德黑兰血脂和血糖研究，136名男性和220名女性纳入研究对照组。平均年龄为28.4岁。患者接受至少1个月正常自由饮食的训练，然后前往实验室。空腹12小时，每隔2小时采集一次血样。高甘油三酯血症定义为男性血浆水平≥160mg/dl，女性≥130mg/dl。高胆固醇血症指其值>200mg/dl。正常高密度脂蛋白水平定义为男性>39mg/dl，女性>35mg/dl。

结果

每位受试者的皮赘平均数量为12.6个。皮赘最常见的部位是颈部和上胸部（平均数量：13.4个，48.9%），其次是腋窝（平均数量：11.6个，33%）和乳房（10.2个，10.1%）。病例组的平均胆固醇水平为192.2±33.1mg/dl，而对照组为187.0±42mg/dl。甘油三酯的平均值±标准差为132.1±69mg/dl，对照组为129±74mg/dl。