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不仅是临床噩梦:法庭上的羊水栓塞

Not only a clinical nightmare: amniotic fluid embolism in court.

作者信息

Busardo Francesco P, Gulino Matteo, Di Luca Natale M, Vergallo Gianluca M, Pacchiarotti Arianna, Frati Paola

机构信息

Department of Anatomical, Histological, Medico-legal and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336 (00185) Rome, Italy.

出版信息

Curr Pharm Biotechnol. 2014;14(14):1195-200. doi: 10.2174/1389201015666140430103312.

Abstract

Amniotic fluid embolism (AFE) is an uncommon obstetric condition involving usually women in labour or in the early post-partum period. Clinical consequences of this unpredictable and unpreventable pathology may be extremely serious with high morbidity and mortality rates. Data obtained from the US Amniotic Fluid Embolism Registry show that the process is more similar to anaphylaxis than to embolism, and the term anaphylactoid syndrome of pregnancy has been suggested because foetal tissue or amniotic fluid components are not universally found in women who present signs and symptoms related to AFE. The first aim of this paper has been to focus on the medico-legal aspects concerning the misdiagnosis and the treatment of the AFE and the Authors, with this purpose in mind, reviewed the main national law cases on medical malpractice claims involving both physicians and hospitals. The second aim has been to highlight the need to introduce a National register as a useful tool to raise the awareness of this disease among physicians and to improve the quality of care, which can be achieved through a proper identification and reporting of AFE cases. The application of a national register may limit the number of medico-legal litigations, which according to the national and foreign Jurisprudence are not currently based in favour of the predictability of AFE, but they focus their discussion on the importance of a prompt medical assistance when the effects of this disorder occur.

摘要

羊水栓塞(AFE)是一种罕见的产科病症,通常发生于分娩期妇女或产后早期。这种不可预测且无法预防的病理状况的临床后果可能极其严重,发病率和死亡率都很高。从美国羊水栓塞登记处获得的数据表明,该过程与过敏反应更为相似,而非栓塞,鉴于出现与AFE相关体征和症状的女性中并非普遍能检测到胎儿组织或羊水成分,因此有人提出了“妊娠类过敏反应综合征”这一术语。本文的首要目的是聚焦于AFE误诊和治疗方面的法医学问题,作者们为此回顾了涉及医生和医院的主要国内医疗事故索赔法律案例。第二个目的是强调有必要设立一个国家登记处,作为提高医生对该疾病认识并改善医疗质量的有用工具,这可通过对AFE病例进行恰当识别和报告来实现。国家登记处的应用可能会限制法医学诉讼的数量,根据国内外判例法,目前这些诉讼并非基于AFE的可预测性,而是将讨论重点放在该病症发作时及时医疗救助的重要性上。

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