Bennadi Darshana
Department of Public Health Dentistry, Sree Siddhartha Dental College and Hospital, Tumkur, Karnataka, India.
J Basic Clin Pharm. 2013 Dec;5(1):19-23. doi: 10.4103/0976-0105.128253.
Self-medication is a global phenomenon and potential contributor to human pathogen resistance to antibiotics. The adverse consequences of such practices should always be emphasized to the community and steps to curb it. Rampant irrational use of antimicrobials without medical guidance may result in greater probability of inappropriate, incorrect, or undue therapy, missed diagnosis, delays in appropriate treatment, pathogen resistance and increased morbidity. This review focused on the self-medication of allopathic drugs, their use, its safety and reason for using it. It would be safe, if the people who are using it, have sufficient knowledge about its dose, time of intake, side effect on over dose, but due to lack of information it can cause serious effects such as antibiotic resistance, skin problem, hypersensitivity and allergy. There is need to augment awareness and implement legislations to promote judicious and safe practices. Improved knowledge and understanding about self-medication may result in rationale use and thus limit emerging microbial resistance issues. Articles which were published in peer reviewed journals, World Self-Medication Industry and World Health Organization websites relating to self-medication reviewed.
自我药疗是一种全球现象，也是导致人类病原体对抗生素产生耐药性的一个潜在因素。应始终向公众强调这种行为的不良后果，并采取措施加以遏制。在没有医疗指导的情况下滥用抗菌药物可能会增加不恰当、错误或过度治疗、漏诊、延误适当治疗、病原体耐药性以及发病率上升的可能性。本综述聚焦于对抗生素类药物的自我药疗、其使用情况、安全性及使用原因。如果使用这些药物的人对其剂量、服用时间、过量服用的副作用有足够了解，那么使用起来是安全的，但由于信息匮乏，它可能会导致诸如抗生素耐药性、皮肤问题、超敏反应和过敏等严重后果。有必要提高认识并实施相关立法，以促进合理、安全用药。增进对自我药疗的认识和理解可能会促使合理用药，从而限制新出现的微生物耐药性问题。对发表在同行评审期刊、世界自我药疗产业组织和世界卫生组织网站上的有关自我药疗的文章进行了综述。
