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Healing of grafted adipose tissue: current clinical applications of adipose-derived stem cells for breast and face reconstruction.移植脂肪组织的愈合：脂肪来源干细胞在乳房和面部重建中的当前临床应用
Wound Repair Regen. 2014 May;22 Suppl 1(0 1):11-3. doi: 10.1111/wrr.12164.
2
Adipose stem cell-based soft tissue regeneration.基于脂肪干细胞的软组织再生。
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本文引用的文献

1
Adipose stem cell-based soft tissue regeneration.基于脂肪干细胞的软组织再生。
Expert Opin Biol Ther. 2012 Feb;12(2):155-63. doi: 10.1517/14712598.2012.644533. Epub 2011 Dec 31.
2
Fat grafting and breast reconstruction with implant: another option for irradiated breast cancer patients.脂肪移植联合假体乳房再造：放疗后乳腺癌患者的另一种选择。
Plast Reconstr Surg. 2012 Feb;129(2):317-329. doi: 10.1097/PRS.0b013e31822b6619.
3
Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells.延长缺氧培养和胰蛋白酶消化可提高人脂肪组织来源干细胞的促血管生成潜能。
Cytotherapy. 2011 Mar;13(3):318-28. doi: 10.3109/14653249.2010.506505. Epub 2010 Aug 26.
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The adipose-derived stem cell: looking back and looking ahead.脂肪源干细胞：回顾与展望。
Mol Biol Cell. 2010 Jun 1;21(11):1783-7. doi: 10.1091/mbc.e09-07-0589. Epub 2010 Apr 7.
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Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention.用脂肪源性再生细胞补充脂肪移植可改善长期移植物留存情况。
Ann Plast Surg. 2010 Feb;64(2):222-8. doi: 10.1097/SAP.0b013e31819ae05c.
6
Improvement of the survival of human autologous fat transplantation by using VEGF-transfected adipose-derived stem cells.利用转染 VEGF 的脂肪来源干细胞提高人自体脂肪移植的成活率。
Plast Reconstr Surg. 2009 Nov;124(5):1437-1446. doi: 10.1097/PRS.0b013e3181babbb6.
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Tissue engineering with adipose-derived stem cells (ADSCs): current and future applications.脂肪来源干细胞（ADSCs）的组织工程：当前和未来的应用。
J Plast Reconstr Aesthet Surg. 2010 Nov;63(11):1886-92. doi: 10.1016/j.bjps.2009.10.028. Epub 2009 Dec 7.
8
Progenitor-enriched adipose tissue transplantation as rescue for breast implant complications.富含祖细胞的脂肪组织移植作为乳房植入物并发症的挽救治疗。
Breast J. 2010 Mar-Apr;16(2):169-75. doi: 10.1111/j.1524-4741.2009.00873.x. Epub 2009 Nov 12.
9
Hypoxia-enhanced wound-healing function of adipose-derived stem cells: increase in stem cell proliferation and up-regulation of VEGF and bFGF.缺氧增强脂肪干细胞的伤口愈合功能：干细胞增殖增加以及血管内皮生长因子（VEGF）和碱性成纤维细胞生长因子（bFGF）上调。
Wound Repair Regen. 2009 Jul-Aug;17(4):540-7. doi: 10.1111/j.1524-475X.2009.00499.x.
10
Autologous fat graft in radiated tissue prior to alloplastic reconstruction of the breast: report of two cases.自体脂肪移植在放射性组织中进行，然后进行乳房的假体重建：两例报告。
Aesthetic Plast Surg. 2010 Feb;34(1):5-10. doi: 10.1007/s00266-009-9367-3. Epub 2009 May 27.

移植脂肪组织的愈合：脂肪来源干细胞在乳房和面部重建中的当前临床应用

Healing of grafted adipose tissue: current clinical applications of adipose-derived stem cells for breast and face reconstruction.

作者信息

Philips Brian J, Marra Kacey G, Rubin J Peter

机构信息

Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.

出版信息

Wound Repair Regen. 2014 May;22 Suppl 1(0 1):11-3. doi: 10.1111/wrr.12164.

DOI:10.1111/wrr.12164
PMID:24813358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4756904/
Abstract

Since their isolation and characterization nearly a decade ago, adipose-derived stem cells (ASCs) have become one of the most popular adult stem cell populations for soft tissue engineering and regenerative medicine applications. Compared with other stem cell sources, ASCs offer several advantages including abundant autologous source, minor invasive harvesting (liposuction), significant proliferative capacity in culture, and multilineage potential. In this mini review, we focus on some of the more salient published clinical and preclinical data to date regarding ASC treatment for breast and facial soft tissue reconstruction.

摘要

自近十年前被分离和鉴定以来，脂肪来源干细胞（ASC）已成为软组织工程和再生医学应用中最受欢迎的成体干细胞群体之一。与其他干细胞来源相比，ASC具有多种优势，包括丰富的自体来源、微创采集（抽脂）、在培养中显著的增殖能力以及多向分化潜能。在本综述中，我们重点关注了迄今为止已发表的一些关于ASC用于乳房和面部软组织重建治疗的更为突出的临床和临床前数据。