移植脂肪组织的愈合：脂肪来源干细胞在乳房和面部重建中的当前临床应用
Healing of grafted adipose tissue: current clinical applications of adipose-derived stem cells for breast and face reconstruction.
作者信息
Philips Brian J, Marra Kacey G, Rubin J Peter
机构信息
Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
出版信息
Wound Repair Regen. 2014 May;22 Suppl 1(0 1):11-3. doi: 10.1111/wrr.12164.
Abstract
Since their isolation and characterization nearly a decade ago, adipose-derived stem cells (ASCs) have become one of the most popular adult stem cell populations for soft tissue engineering and regenerative medicine applications. Compared with other stem cell sources, ASCs offer several advantages including abundant autologous source, minor invasive harvesting (liposuction), significant proliferative capacity in culture, and multilineage potential. In this mini review, we focus on some of the more salient published clinical and preclinical data to date regarding ASC treatment for breast and facial soft tissue reconstruction.
摘要
自近十年前被分离和鉴定以来，脂肪来源干细胞（ASC）已成为软组织工程和再生医学应用中最受欢迎的成体干细胞群体之一。与其他干细胞来源相比，ASC具有多种优势，包括丰富的自体来源、微创采集（抽脂）、在培养中显著的增殖能力以及多向分化潜能。在本综述中，我们重点关注了迄今为止已发表的一些关于ASC用于乳房和面部软组织重建治疗的更为突出的临床和临床前数据。
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