波多黎各艾滋病患者中与人乳头瘤病毒相关的癌症
Human papillomavirus-related cancers among people living with AIDS in Puerto Rico.
作者信息
Ortiz Ana Patricia, Pérez-Irizarry Javier, Soto-Salgado Marievelisse, Suárez Erick, Pérez Naydi, Cruz Maritza, Palefsky Joel, Tortolero-Luna Guillermo, Miranda Sandra, Colón-López Vivian
机构信息
University of Puerto Rico Comprehensive Cancer Center and Graduate School of Public Health, University of Puerto Rico, PMB 711, 89 De Diego Ave, Suite 105, San Juan, PR 00927-6346. Telephone: 787-772-8300, Ext 1204. E-mail:
University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
出版信息
Prev Chronic Dis. 2014 May 15;11:E80. doi: 10.5888/pcd11.130361.
The objective of this study was to estimate the incidence of cancer and human papillomavirus (HPV)-related cancers and the risk of death (by cancer status) among people living with AIDS (PLWA) in Puerto Rico. We used data from the Puerto Rico AIDS Surveillance Program and Central Cancer Registry (1985-2005). Cancers with highest incidence were cervix (299.6/100,000) for women and oral cavity/oropharynx for men (150.0/100,000); the greatest excess of cancer incidence for men (standardized incidence ratio, 86.8) and women (standardized incidence ratio, 52.8) was for anal cancer. PLWA who developed a cancer had decreased survival and increased risk of death compared with those who did not have cancer. Cancer control strategies for PLWA will be essential for improving their disease survival.
本研究的目的是估计波多黎各艾滋病患者（PLWA）中癌症及人乳头瘤病毒（HPV）相关癌症的发病率，以及（按癌症状态划分的）死亡风险。我们使用了波多黎各艾滋病监测项目和中央癌症登记处（1985 - 2005年）的数据。女性中发病率最高的癌症是子宫颈癌（299.6/10万），男性中是口腔/口咽癌（150.0/10万）；男性（标准化发病率比为86.8）和女性（标准化发病率比为52.8）中癌症发病率超出最多的是肛门癌。与未患癌症的艾滋病患者相比，患癌的艾滋病患者生存率降低，死亡风险增加。针对艾滋病患者的癌症控制策略对于提高他们的疾病生存率至关重要。
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