Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain.
Bioinformatics Andalusian Platform, Bio-innovation Building, University of Malaga, 29590 Málaga, Spain.
Biology (Basel). 2012 Sep 18;1(2):439-59. doi: 10.3390/biology1020439.
In spite of the biological and economic importance of plants, relatively few plant species have been sequenced. Only the genome sequence of plants with relatively small genomes, most of them angiosperms, in particular eudicots, has been determined. The arrival of next-generation sequencing technologies has allowed the rapid and efficient development of new genomic resources for non-model or orphan plant species. But the sequencing pace of plants is far from that of animals and microorganisms. This review focuses on the typical challenges of plant genomes that can explain why plant genomics is less developed than animal genomics. Explanations about the impact of some confounding factors emerging from the nature of plant genomes are given. As a result of these challenges and confounding factors, the correct assembly and annotation of plant genomes is hindered, genome drafts are produced, and advances in plant genomics are delayed.
尽管植物具有重要的生物学和经济意义，但已测序的植物物种相对较少。只有少数基因组较小的植物物种的基因组序列被确定，其中大多数是被子植物，特别是真双子叶植物。新一代测序技术的出现使得为非模式或孤儿植物物种快速高效地开发新的基因组资源成为可能。但是，植物的测序速度远远落后于动物和微生物。这篇综述重点介绍了植物基因组的典型挑战，这些挑战可以解释为什么植物基因组学的发展不如动物基因组学。文中还解释了一些由植物基因组特性带来的干扰因素的影响。由于这些挑战和干扰因素的存在，植物基因组的正确组装和注释受到阻碍，导致产生基因组草图，植物基因组学的进展也因此被延迟。
