Szathmáry E, Gladkih I
Department of Plant Taxonomy and Ecology, Roland Eötvös University, Budapest, Hungary.
J Theor Biol. 1989 May 9;138(1):55-8. doi: 10.1016/s0022-5193(89)80177-8.
The experimentally reported kinetic behaviour (sub-exponential but supra-linear growth) of non-enzymatic template replication is incorporated into a simple model of template competition. Sub-exponential growth is shown to lead to coexistence invariably. Thus coexistence of different non-enzymatically replicating sequences is predicted. This type of coexistence could have been important in maintaining a sufficient diversity of RNA modules used later to build functional molecules such as ribozymes. Experimental tests of this theoretical prediction are possible.
实验报道的非酶模板复制的动力学行为（亚指数但超线性增长）被纳入一个简单的模板竞争模型。结果表明，亚指数增长总是导致共存。因此，预测了不同非酶复制序列的共存。这种共存类型对于维持后来用于构建诸如核酶等功能分子的RNA模块的足够多样性可能很重要。对这一理论预测进行实验验证是可行的。
