Faculty of Medicine, Zagazig University, Egypt, 18 Omar Bin Elkhattab St, Al Qawmia, Zagazig City, Al Sharqia Governorate, Egypt.
Infect Dis Poverty. 2014 Apr 24;3:14. doi: 10.1186/2049-9957-3-14. eCollection 2014.
Community-acquired pneumonia (CAP) is one of the five leading causes of death among children in developing countries, accounting for approximately three million deaths per year. Identification of the modifiable risk factors of CAP may help to reduce the burden of this disease. In this study, the impact of the socioeconomic status (SES) on the severity and outcome of CAP among Egyptian children was studied.
This was a prospective longitudinal cohort study which included 1,470 children diagnosed with CAP, aged two to 15 years (median age 5.4 years). The diagnosis of CAP was based on clinical and radiological findings. A structured questionnaire and the patients' medical records were used for the data collection. The subjects were divided into two groups: mild and severe CAP. Social and demographic variables were compared, and a multivariate logistic regression analysis was performed.
THE MULTIVARIATE ANALYSIS SHOWED THAT A LOW MATERNAL EDUCATION LEVEL (OR: 3.8; 95% CI: 2.12 -6.70; P = .0001), unavailability of adequate medical care (OR: 3.1; 95% CI: 1.99 -4.88; P = .0001), a low family income (OR: 2.2; 95% CI: 0.99 -4.78; P = .047), and parents' smoking habits (OR: 2.0; 95% CI: 1.15 -3.55; P = .014) were significant independent predictive risk factors for severe CAP among Egyptian children.
Public health measures against these socio-demographic risk factors should be identified as priorities in order to help reduce the disease burden of deaths from severe CAP among Egyptian children.
社区获得性肺炎（CAP）是发展中国家儿童死亡的五个主要原因之一，每年约有 300 万人死亡。确定 CAP 的可改变危险因素可能有助于减轻该疾病的负担。在这项研究中，研究了埃及儿童的社会经济状况（SES）对 CAP 的严重程度和结局的影响。
这是一项前瞻性纵向队列研究，共纳入 1470 例年龄在 2 至 15 岁（中位数年龄 5.4 岁）的 CAP 患儿。CAP 的诊断基于临床和影像学发现。使用结构化问卷和患者病历进行数据收集。将研究对象分为轻度和重度 CAP 两组。比较社会人口学变量，并进行多变量逻辑回归分析。
多变量分析显示，母亲教育程度低（OR：3.8；95%CI：2.12-6.70；P=0.0001）、无法获得足够的医疗保健（OR：3.1；95%CI：1.99-4.88；P=0.0001）、家庭收入低（OR：2.2；95%CI：0.99-4.78；P=0.047）和父母吸烟习惯（OR：2.0；95%CI：1.15-3.55；P=0.014）是埃及儿童重度 CAP 的显著独立预测危险因素。
应确定针对这些社会人口学危险因素的公共卫生措施作为优先事项，以帮助减轻埃及儿童因重度 CAP 导致的疾病负担。
