Barsukov V S
Zh Mikrobiol Epidemiol Immunobiol. 1989 Dec(12):68-74.
Experiments on CBA and (CBA X C57BL)F1 mice have revealed that a prolonged period of antigen-nonspecific immunosuppression of humoral immunity develops in experimental staphylococcal infection; this period of suppression may be preceded by a short phase of antigen-nonspecific immunostimulation. Immunosuppression is linked with the accumulation of antigen-nonspecific T-suppressors in the spleen, these T-suppressors being capable of the manifestation of their activity both in vitro and in vivo in cases of their transplantation to semi-syngeneic recipients. Immunosuppression does not aggravate the course of staphylococcal infection and is accompanied by an increase in resistance to Pseudomonas aeruginosa superinfection, which is due to the stimulation of inflammatory reaction at the site of the injection of the superinfecting agent.
对CBA小鼠和（CBA×C57BL）F1小鼠进行的实验表明，在实验性葡萄球菌感染中会出现长时间的体液免疫抗原非特异性免疫抑制；在此抑制期之前可能会有一个短暂的抗原非特异性免疫刺激阶段。免疫抑制与脾脏中抗原非特异性T抑制细胞的积累有关，这些T抑制细胞在移植到半同基因受体的情况下，能够在体外和体内表现出其活性。免疫抑制不会加重葡萄球菌感染的病程，并且伴随着对铜绿假单胞菌重叠感染抵抗力的增加，这是由于在重叠感染病原体注射部位的炎症反应受到刺激所致。
