Gusev E Iu, Ponosov V L
Zh Mikrobiol Epidemiol Immunobiol. 1993 Mar-Apr(2):122-4.
In experiments made on noninbred white mice the manifestations of delayed hypersensitivity and the number of antibody-producing cells in regional lymph nodes or the spleen were determined on day 5 after the subcutaneous or intraperitoneal immunization of the animals with sheep red blood cells (SRBC). At the same time the injection of S. aureus antigens simultaneously with SRBC raises the threshold of antigenic sensitivity and decreases the manifestations of cell-mediated and humoral immune response to SRBC. This suppressive effect was even more pronounced in the local immune process and was partially mediated by the hyperproduction of prostaglandins.
在用非近交系白色小鼠进行的实验中，在动物经皮下或腹腔注射绵羊红细胞（SRBC）免疫后的第5天，测定迟发型超敏反应的表现以及局部淋巴结或脾脏中抗体产生细胞的数量。同时，与SRBC同时注射金黄色葡萄球菌抗原会提高抗原敏感性阈值，并降低对SRBC的细胞介导和体液免疫反应的表现。这种抑制作用在局部免疫过程中更为明显，并且部分是由前列腺素的过度产生介导的。
