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慢性阻塞性肺疾病肺康复的成本效益:一项随机对照试验。

Costs and benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease: a randomized controlled trial.

机构信息

Physical Therapy Department, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

Physical Therapy Department, Universidade Federal de Pernambuco, Recife, PE, Brazil.

出版信息

Braz J Phys Ther. 2014 Mar-Apr;18(2):165-73. doi: 10.1590/s1413-35552012005000151. Epub 2014 May 2.

DOI:10.1590/s1413-35552012005000151
PMID:24838809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4183253/
Abstract

OBJECTIVE

The current study evaluated the costs and benefits of a simple aerobic walking program for patients with chronic obstructive pulmonary disease (COPD).

METHOD

This was a blinded randomized controlled clinical trial that recruited 72 patients diagnosed with COPD, 40 of whom were included in the study and divided into two groups [control group (CG) and pulmonary rehabilitation group (GPR)]. We assessed pulmonary function, distance covered during the 6-minute walk test (6MWT), respiratory and peripheral muscle strength, health-related quality of life (HRQOL), body composition, and level of activities of daily living (ADLs) before and after an 8-week walking program. The financial costs were calculated according to the pricing table of the Brazilian Unified Health System (SUS).

RESULTS

Only 34 of the 40 patients remained in the final sample; 16 in the CG and 18 in the GPR (FEV1: 50.9 ± 14% predicted and FEV1: 56 ± 0.5% predicted, respectively). The intervention group exhibited improvements in the 6MWT, sensation of dyspnea and fatigue, work performed, BODE index (p<0.01), HRQOL, ADL level (p<0.001), and lower limb strength (p<0.05). The final mean cost per patient for the GPR was R$ 148.75 (US$ 75.00) and no patient significantly exceeded this value. However, 2 patients in the CG did exceed this value, incurring a cost of R$ 689.15 (US$ 345.00).

CONCLUSION

Aerobic walking demonstrated significant clinical benefits in a cost-efficient manner in patients with COPD.

摘要

目的

本研究评估了慢性阻塞性肺疾病(COPD)患者简单有氧运动方案的成本效益。

方法

这是一项盲法随机对照临床试验,共招募了 72 名确诊为 COPD 的患者,其中 40 名患者入组并分为两组[对照组(CG)和肺康复组(GPR)]。我们在 8 周步行方案前后评估了肺功能、6 分钟步行试验(6MWT)所覆盖的距离、呼吸和外周肌肉力量、健康相关生活质量(HRQOL)、身体成分和日常生活活动(ADL)水平。根据巴西统一医疗保健系统(SUS)的定价表计算了财务成本。

结果

只有 40 名患者中的 34 名患者留在最终样本中;CG 组 16 名,GPR 组 18 名(FEV1:分别为 50.9 ± 14%预测和 56 ± 0.5%预测)。干预组在 6MWT、呼吸困难和疲劳感觉、工作能力、BODE 指数(p<0.01)、HRQOL、ADL 水平(p<0.001)和下肢力量方面均有改善(p<0.05)。GPR 组每名患者的最终平均治疗费用为 148.75 雷亚尔(约 75.00 美元),没有患者显著超过这一数值。但是,CG 组的 2 名患者超过了这一数值,花费了 689.15 雷亚尔(约 345.00 美元)。

结论

有氧运动在 COPD 患者中以具有成本效益的方式显示出显著的临床益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c2f/4183253/6a15ee9f3d71/rbfis-18-02-0165-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c2f/4183253/6a15ee9f3d71/rbfis-18-02-0165-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c2f/4183253/6a15ee9f3d71/rbfis-18-02-0165-g01.jpg

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