Galushko Maren, Strupp Julia, Walisko-Waniek Johanna, Hahn Moritz, Löffert Sabine, Ernstmann Nicole, Pfaff Holger, Radbruch Lukas, Nauck Friedemann, Ostgathe Christoph, Voltz Raymond
Department of Palliative Medicine,University Hospital of Cologne,Cologne,Germany.
Institute for Medical Statistics and Epidemiology,University Hospital of Cologne,Cologne,Germany.
Palliat Support Care. 2015 Jun;13(3):713-23. doi: 10.1017/S1478951514000492. Epub 2014 May 22.
Reliable and validated instruments are needed in order to study the desire for hastened death (DHD). As there is no instrument in the German language to measure DHD, our aim was to validate a German version of the Schedule of Attitudes Toward Hastened Death (SAHD-D).
The SAHD was translated following guidelines promulgated by the European Organization for Research and Treatment of Cancer (EORTC). In eligible patients (clinical situation adequate, MMSE ≥21), the following instruments were employed: a symptom checklist (HOPE), the HADS-D (Hospital Anxiety and Depression Scale), the EORTC-QLQ-PAL15, and the SAHD-D, as well as an external estimation of DHD provided by the attending physician. A high level of DHD was defined as the mean plus one standard deviation (SD).
Of the 869 patients assessed, 92 were eligible for inclusion (66% females, mean age of 64.5 years). The SAHD-D total score ranged from 0 to 18, with a mean of 5 and a standard deviation (SD) of 3.7. A high level of DHD was found in 20% (n = 19). For discriminant validity, significant correlations were found between the SAHD-D and depression (r rho = 0.472), anxiety (r rho = 0.224), and clinical state (r rho = 0.178). For criterion validity, the external estimate of DHD showed a low significant correlation with patient score (r rho = 0.290). Factor analysis of the SAHD-D identified two factors.
Validation of the SAHD-D illustrated good discriminant validity, confirming that a desire to hasten death is a construct separate from depression, anxiety, or physical state. The unidimensionality of the SAHD could not be reproduced. Our findings support the multifactorial interdependencies on DHD and suggest that the SAHD-D should be refined by considering actual wishes, general attitudes, and options of patients.
为了研究加速死亡愿望(DHD),需要可靠且经过验证的工具。由于德语中没有用于测量DHD的工具,我们的目标是验证德语版的加速死亡态度量表(SAHD-D)。
按照欧洲癌症研究与治疗组织(EORTC)颁布的指南对SAHD进行翻译。在符合条件的患者(临床情况合适,MMSE≥21)中,使用了以下工具:症状清单(HOPE)、医院焦虑抑郁量表(HADS-D)、EORTC-QLQ-PAL15、SAHD-D,以及主治医生对DHD的外部评估。将高水平的DHD定义为平均值加一个标准差(SD)。
在评估的869名患者中,92名符合纳入条件(66%为女性,平均年龄64.5岁)。SAHD-D总分范围为0至18,平均值为5,标准差(SD)为3.7。20%(n = 19)的患者存在高水平的DHD。在区分效度方面,发现SAHD-D与抑郁(r rho = 0.472)、焦虑(r rho = )之间存在显著相关性。