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通过左腹股沟斜疝发现的内脏利什曼病一例:病例报告

A case of visceral leishmaniasis found by left oblique hernia: A case report.

作者信息

Zhang Guoqiang, Zhong Jihua, Wang Ting, Zhong Lu

机构信息

Department of Hematology, Renji Hospital, Medical College, Shanghai Jiaotong University, Shanghai 200001, P.R. China.

出版信息

Exp Ther Med. 2020 Apr;19(4):2697-2701. doi: 10.3892/etm.2020.8487. Epub 2020 Feb 4.

DOI:10.3892/etm.2020.8487
PMID:32256751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7086162/
Abstract

Visceral leishmaniasis (VL) is an infectious disease caused by protozoa. Since sporadic cases of this disease are noted in non-endemic areas and are associated with a limited outbreak, the disease is easily overlooked. In addition, other illnesses exhibit similar symptoms. It is difficult for clinicians to establish an accurate diagnosis and develop effective treatments for this disease. The present study reported a case of a 25-year-old young man admitted to the hospital due to oblique hernia. The case was diagnosed as VL. The patient presented with persistent night sweats and fatigue as described in his admission history. However, the body temperature was normal. Routine examination revealed that the patient exhibited chronic hepatitis B infection, pancytopenia, hepatosplenomegaly, increased erythrocyte sedimentation rate, significant plasma cell infiltration in bone marrow aspirate and hypergammaglobulinemia. The retrospective analysis of the present case can improve the diagnostic accuracy and treatment rate of VL in non-epidemic areas.

摘要

内脏利什曼病(VL)是一种由原生动物引起的传染病。由于这种疾病的散发病例在非流行地区被发现,且与有限的疫情爆发相关,该疾病很容易被忽视。此外,其他疾病也表现出类似症状。临床医生很难对这种疾病进行准确诊断并制定有效的治疗方案。本研究报告了一例25岁因腹股沟斜疝入院的青年男性病例。该病例被诊断为内脏利什曼病。患者如入院病史所述,出现持续盗汗和疲劳症状。然而,体温正常。常规检查显示患者患有慢性乙型肝炎感染、全血细胞减少、肝脾肿大、红细胞沉降率升高、骨髓穿刺涂片有明显浆细胞浸润以及高球蛋白血症。对本病例的回顾性分析可以提高非流行地区内脏利什曼病的诊断准确性和治疗率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/4b936b9ce736/etm-19-04-2697-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/be77a01a572d/etm-19-04-2697-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/61c54ba35a7a/etm-19-04-2697-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/4b936b9ce736/etm-19-04-2697-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/be77a01a572d/etm-19-04-2697-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/61c54ba35a7a/etm-19-04-2697-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/909f/7086162/4b936b9ce736/etm-19-04-2697-g02.jpg

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Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients.建立一种夹心 ELISA 检测内脏利什曼病患者血液样本中的利什曼原虫 40S 核糖体蛋白 S12 抗原。
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Leishmaniasis.
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Molecular Diagnosis of Visceral Leishmaniasis.内脏利什曼病的分子诊断。
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