Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Diabetes Metab J. 2014 Apr;38(2):150-7. doi: 10.4093/dmj.2014.38.2.150. Epub 2014 Apr 18.
The aim of this study was to identify factors associated with mild cognitive impairment (MCI) in older Korean adults with type 2 diabetes mellitus.
A total of 226 older (age ≥65 years) adults without a history of cerebrovascular disease or dementia participated in this study. Cognitive function was assessed with the Montreal Cognitive Assessment-Korean version (MoCA-K). A MoCA-K score <23 was defined as MCI.
The prevalence of MCI was 32.7%. In a logistic regression analysis, age (≥74 years old vs. 65-68 years old; odds ratio [OR], 3.69; 95% confidence interval [CI], 1.55 to 8.82; P=0.003), educational background (college graduation vs. no school or elementary school graduation; OR, 0.16; 95% CI, 0.05 to 0.46; P=0.001), and systolic blood pressure (≥135 mm Hg vs. ≤120 mm Hg; OR, 3.25; 95% CI, 1.29 to 8.17; P=0.012) were associated with MCI.
More concentrated efforts focused on early detection and appropriate management of MCI may be required in older Korean adults with type 2 diabetes mellitus.
本研究旨在确定与 2 型糖尿病老年韩国成年人轻度认知障碍（MCI）相关的因素。
共有 226 名无脑血管疾病或痴呆病史的老年（年龄≥65 岁）成年人参与了本研究。认知功能采用蒙特利尔认知评估-韩国版（MoCA-K）进行评估。MoCA-K 评分<23 定义为 MCI。
MCI 的患病率为 32.7%。在逻辑回归分析中，年龄（≥74 岁与 65-68 岁；比值比 [OR]，3.69；95%置信区间 [CI]，1.55 至 8.82；P=0.003）、教育背景（大学毕业与未上学或小学毕业；OR，0.16；95%CI，0.05 至 0.46；P=0.001）和收缩压（≥135mmHg 与≤120mmHg；OR，3.25；95%CI，1.29 至 8.17；P=0.012）与 MCI 相关。
需要对 2 型糖尿病老年韩国成年人更加集中精力，早期发现并适当管理 MCI。
