Tokarevich N K, Daĭter A B, Lukacheva M, Kartseva N A
Tr Inst Im Pastera. 1989;66:110-8, 172-3.
It is proved that the challenging of the extract isolated from Coxiella (as a result of treatment with the mixture of chloroform and methanol) to animals doesn't provoke the appearance of antibodies to these microorganisms. It also doesn't cause the sensibilization of lymphocytes to Coxiella, but the extract can interact specifically with a serum containing antibodies to Coxiella. It permits to characterise the tested extract of Coxiella as a hapten with properties of adjuvant because it stimulates antibody-appearance.
已证实，从柯克斯体中分离出的提取物（经氯仿和甲醇混合处理）对动物进行攻击时，不会引发针对这些微生物的抗体出现。它也不会导致淋巴细胞对柯克斯体产生致敏，但该提取物可与含有抗柯克斯体抗体的血清发生特异性相互作用。这使得可以将所测试的柯克斯体提取物表征为具有佐剂特性的半抗原，因为它能刺激抗体产生。
