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小儿扩张型心肌病桥接移植/恢复的替代策略

An Alternative Strategy for Bridge-to-Transplant/Recovery in Small Children with Dilated Cardiomyopathy.

作者信息

Mets Gilles, Panzer Joseph, De Wolf Daniël, Bové Thierry

机构信息

Department of Pediatrics, University Hospital of Ghent, Ghent, Belgium.

Department of Pediatric Cardiology, University Hospital of Ghent, Ghent, Belgium.

出版信息

Pediatr Cardiol. 2017 Jun;38(5):902-908. doi: 10.1007/s00246-017-1610-0. Epub 2017 Mar 29.

DOI:10.1007/s00246-017-1610-0
PMID:28357450
Abstract

Dilated cardiomyopathy in children still has a poor prognosis with high rates of mortality and cardiac transplantation (resp. around 20 and 25%). Awaiting transplantation or possible recovery, these pediatric patients are mechanically supported with extracorporeal membrane oxygenation or a paracorporeal ventricular assist device, both resulting in higher survival rates but also entailing considerable risks of infection, thrombosis, or bleeding. A new indication for an old technique, i.e., pulmonary artery banding, presents itself as an interesting alternative to mechanical circulatory support in selected infants and small children with dilated LV cardiomyopathy and preserved RV function. Here we present a brief review of literature and report on two patients in whom PAB has been successfully implemented as either bridge-to-recovery or bridge-to-transplant.

摘要

儿童扩张型心肌病的预后仍然很差,死亡率和心脏移植率很高(分别约为20%和25%)。在等待移植或可能康复期间,这些儿科患者通过体外膜肺氧合或体外心室辅助装置进行机械支持,这两种方法都能提高生存率,但也带来了感染、血栓形成或出血的巨大风险。一种旧技术——肺动脉环扎术的新适应证,成为了在选定的患有扩张型左心室心肌病且右心室功能保留的婴儿和年幼儿童中替代机械循环支持的有趣选择。在此,我们简要回顾文献,并报告两例成功实施肺动脉环扎术作为过渡到康复或过渡到移植的患者。

相似文献

1
An Alternative Strategy for Bridge-to-Transplant/Recovery in Small Children with Dilated Cardiomyopathy.小儿扩张型心肌病桥接移植/恢复的替代策略
Pediatr Cardiol. 2017 Jun;38(5):902-908. doi: 10.1007/s00246-017-1610-0. Epub 2017 Mar 29.
2
Successful bridge to transplant using the Berlin Heart left ventricular assist device in a 3-month-old infant.在一名3个月大的婴儿中使用柏林心脏左心室辅助装置成功过渡到移植。
Ann Thorac Surg. 2006 Mar;81(3):1116-8. doi: 10.1016/j.athoracsur.2005.01.045.
3
Pulmonary artery banding in infants and young children with left ventricular dilated cardiomyopathy: a novel therapeutic strategy before heart transplantation.肺动脉环缩术治疗左心室扩张型心肌病婴幼儿:心脏移植前的一种新的治疗策略。
J Heart Lung Transplant. 2013 May;32(5):475-81. doi: 10.1016/j.healun.2013.01.988. Epub 2013 Feb 12.
4
Ventricular assist device support in children and adolescents as a bridge to heart transplantation.儿童和青少年使用心室辅助装置作为心脏移植的桥梁。
Ann Thorac Surg. 2006 Sep;82(3):926-32. doi: 10.1016/j.athoracsur.2006.02.087.
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Surgical strategies for the management of end-stage heart failure in infants and children: A 15-year experience with a patient-tailored approach.婴儿和儿童终末期心力衰竭的外科治疗策略:采用个体化方法的 15 年经验。
Artif Organs. 2021 Dec;45(12):1543-1553. doi: 10.1111/aor.14057. Epub 2021 Sep 12.
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Minimally invasive mechanical cardiac support without extracorporeal membrane oxygenation in children awaiting heart transplantation.在等待心脏移植的儿童中,无需体外膜肺氧合的微创机械心脏支持。
Ann Thorac Surg. 1999 Dec;68(6):2320-3. doi: 10.1016/s0003-4975(99)01049-8.
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Left ventricular assist for pediatric patients with dilated cardiomyopathy using the Medos VAD cannula and a centrifugal pump.使用 Medos VAD 插管和离心泵为扩张型心肌病的儿科患者提供左心室辅助。
Artif Organs. 2009 Nov;33(11):1032-7. doi: 10.1111/j.1525-1594.2009.00936.x.
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Ventricular assist devices as a bridge-to-transplant improve early post-transplant outcomes in children.作为移植桥梁的心室辅助装置可改善儿童移植后的早期预后。
J Heart Lung Transplant. 2014 Jul;33(7):704-12. doi: 10.1016/j.healun.2014.02.010. Epub 2014 Feb 14.
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Cardiac extracorporeal life support: state of the art in 2007.心脏体外生命支持:2007年的技术现状
Cardiol Young. 2007 Sep;17 Suppl 2:104-15. doi: 10.1017/S1047951107001217.
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The impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation.桥接心脏移植的心室辅助装置支持对心脏移植后生存率的影响。
J Thorac Cardiovasc Surg. 2010 Jul;140(1):169-73. doi: 10.1016/j.jtcvs.2010.03.026. Epub 2010 May 7.

引用本文的文献

1
Revived Role of Pulmonary Artery Band in Management of Heart Failure in Pediatric Dilated Cardiomyopathy.肺动脉环扎术在小儿扩张型心肌病心力衰竭治疗中的复兴作用
Pediatr Cardiol. 2024 Oct 19. doi: 10.1007/s00246-024-03685-5.
2
Feasibility of the Omaha system for the care of children with dilated cardiomyopathy.奥马哈系统用于扩张型心肌病患儿护理的可行性
Front Pediatr. 2023 May 30;11:1136663. doi: 10.3389/fped.2023.1136663. eCollection 2023.
3
Functional regeneration of dilated cardiomyopathy by transcatheter bilateral pulmonary artery banding: first-in-human case series.

本文引用的文献

1
Left ventricular assist devices-current state and perspectives.左心室辅助装置——现状与展望
J Thorac Dis. 2016 Aug;8(8):E660-6. doi: 10.21037/jtd.2016.07.13.
2
Successful HeartWare Bridge to Recovery in a 3-Year Old: A Game Changer?3岁患儿成功使用HeartWare实现康复:是重大突破吗?
Ann Thorac Surg. 2016 May;101(5):1984-7. doi: 10.1016/j.athoracsur.2015.07.067.
3
Pediatric ventricular assist devices.小儿心室辅助装置
经导管双侧肺动脉环缩术治疗扩张型心肌病的功能再生:首例人体病例系列研究
Eur Heart J Case Rep. 2023 Jan 31;7(2):ytad052. doi: 10.1093/ehjcr/ytad052. eCollection 2023 Feb.
4
Changes of serum uric acid and its clinical correlation in children with dilated cardiomyopathy.扩张型心肌病患儿血清尿酸的变化及其临床相关性
Transl Pediatr. 2021 Dec;10(12):3211-3217. doi: 10.21037/tp-21-537.
5
Ethical and practical dilemmas in cardiac transplantation in infants: a literature review.婴儿心脏移植中的伦理和实践困境:文献综述。
Eur J Pediatr. 2021 Aug;180(8):2359-2365. doi: 10.1007/s00431-021-04100-4. Epub 2021 May 6.
6
Pulmonary Artery Banding for Ventricular Rehabilitation in Infants With Dilated Cardiomyopathy: Early Results in a Single-Center Experience.肺动脉环缩术用于扩张型心肌病婴儿的心室康复:单中心经验的早期结果
Front Pediatr. 2020 Jul 16;8:347. doi: 10.3389/fped.2020.00347. eCollection 2020.
J Thorac Dis. 2015 Dec;7(12):2194-202. doi: 10.3978/j.issn.2072-1439.2015.12.61.
4
The Registry of the International Society for Heart and Lung Transplantation: Eighteenth Official Pediatric Heart Transplantation Report--2015; Focus Theme: Early Graft Failure.国际心肺移植学会注册处:2015年第十八份官方小儿心脏移植报告;重点主题:早期移植物功能衰竭
J Heart Lung Transplant. 2015 Oct;34(10):1233-43. doi: 10.1016/j.healun.2015.08.002. Epub 2015 Aug 28.
5
Outpatient management of intra-corporeal left ventricular assist device system in children: a multi-center experience.儿童体内左心室辅助装置系统的门诊管理:多中心经验。
Am J Transplant. 2015 Feb;15(2):453-60. doi: 10.1111/ajt.13003. Epub 2015 Jan 21.
6
Pediatric heart transplant waiting list mortality in the era of ventricular assist devices.儿科心脏移植等待名单在心室辅助设备时代的死亡率。
J Heart Lung Transplant. 2015 Jan;34(1):82-88. doi: 10.1016/j.healun.2014.09.018. Epub 2014 Oct 14.
7
VAD as bridge to recovery in anthracycline-induced cardiomyopathy and HHV6 myocarditis.VAD 作为蒽环类药物诱导性心肌病和 HHV6 心肌炎的恢复桥接。
Pediatrics. 2014 Sep;134(3):e894-9. doi: 10.1542/peds.2013-2272. Epub 2014 Aug 4.
8
Mechanical circulatory support for infants and small children.婴幼儿的机械循环支持
Arch Cardiovasc Dis. 2014 Jun-Jul;107(6-7):398-405. doi: 10.1016/j.acvd.2014.04.006. Epub 2014 Jun 25.
9
Pediatric heart allocation and transplantation in Eurotransplant.欧洲移植组织中的小儿心脏分配与移植
Transpl Int. 2014 Sep;27(9):917-25. doi: 10.1111/tri.12356. Epub 2014 Jun 23.
10
Ventricular assist devices in children.儿童心室辅助装置。
Curr Opin Cardiol. 2014 Jan;29(1):113-21. doi: 10.1097/HCO.0000000000000030.