Ohm Robin A, Riley Robert, Salamov Asaf, Min Byoungnam, Choi In-Geol, Grigoriev Igor V
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States.
US Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, United States.
Fungal Genet Biol. 2014 Nov;72:82-90. doi: 10.1016/j.fgb.2014.05.001. Epub 2014 May 20.
Woody plants convert the energy of the sun into lignocellulosic biomass, which is an abundant substrate for bioenergy production. Fungi, especially wood decayers from the class Agaricomycetes, have evolved ways to degrade lignocellulose into its monomeric constituents, and understanding this process may facilitate the development of biofuels. Over the past decade genomics has become a powerful tool to study the Agaricomycetes. In 2004 the first sequenced genome of the white rot fungus Phanerochaete chrysosporium revealed a rich catalog of lignocellulolytic enzymes. In the decade that followed the number of genomes of Agaricomycetes grew to more than 75 and revealed a diversity of wood-decaying strategies. New technologies for high-throughput functional genomics are now needed to further study these organisms.
木本植物将太阳能转化为木质纤维素生物质，这是一种丰富的生物能源生产底物。真菌，尤其是伞菌纲的木材腐朽菌，已经进化出将木质纤维素降解为其单体成分的方法，了解这一过程可能有助于生物燃料的开发。在过去十年中，基因组学已成为研究伞菌纲的强大工具。2004年，白腐真菌黄孢原毛平革菌的首个测序基因组揭示了丰富的木质纤维素分解酶目录。在随后的十年中，伞菌纲的基因组数量增长到75个以上，并揭示了多种木材腐朽策略。现在需要高通量功能基因组学的新技术来进一步研究这些生物体。
