两例新生儿人细小病毒3型脑炎
Two cases of neonatal human parechovirus 3 encephalitis.
作者信息
Pariani Elena, Pellegrinelli Laura, Pugni Lorenza, Bini Paolo, Perniciaro Simona, Bubba Laura, Primache Valeria, Amendola Antonella, Barbarini Mario, Mosca Fabio, Binda Sandro
机构信息
From the *Department of Biomedical Sciences for Health; †Neonatal Intensive Care Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan; and ‡Neonatal Intensive Care Unit, General Hospital "Azienda Ospedaliera Sant'Anna", Como, Italy.
出版信息
Pediatr Infect Dis J. 2014 Nov;33(11):1191-3. doi: 10.1097/INF.0000000000000412.
We report 2 neonates with human parechoviruses type 3 encephalitis. Both newborns presented with fever, irritability and seizures. Cerebrospinal fluid analyses were normal, but magnetic resonance imaging revealed white matter damage, suggesting human parechoviruse infection. Human parechoviruses type 3-RNA was detected in cerebrospinal fluid samples and in blood, stool, urine and respiratory samples, indicating the dissemination of the virus.
我们报告了2例3型人副肠道病毒脑炎新生儿病例。两名新生儿均出现发热、易激惹和惊厥症状。脑脊液分析结果正常，但磁共振成像显示存在白质损伤，提示为人副肠道病毒感染。在脑脊液样本以及血液、粪便、尿液和呼吸道样本中均检测到3型人副肠道病毒RNA，表明该病毒发生了播散。
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