Buluş Ayşe Derya, Andıran Nesibe, Koçak Mesut
J Pediatr Endocrinol Metab. 2014 Sep;27(9-10):977-81. doi: 10.1515/jpem-2013-0262.
Iatrogenic Cushing's syndrome in children may occur as a result of the application of exogenous steroids. Prolonged use of powerful corticosteroids suppresses adrenal functions and iatrogenic Cushing's syndrome may develop particularly in infants who are given topical corticosteroids. We report here a case on three infants having Cushing's syndrome with similar clinical presentations due to overuse of topical steroids for diaper dermatitis. The importance of exercising caution during the use of topical steroids is underlined in this study.
儿童医源性库欣综合征可能是由于应用外源性类固醇所致。长期使用强效皮质类固醇会抑制肾上腺功能,医源性库欣综合征可能尤其在使用局部皮质类固醇的婴儿中发生。我们在此报告3例因过度使用局部类固醇治疗尿布皮炎而出现类似临床表现的库欣综合征婴儿病例。本研究强调了在使用局部类固醇时谨慎行事的重要性。