Li Tie, Shen Jianfeng, Li Na, Ye Mingxin
Center of Special Materials and Technology, Fudan University, Shanghai 200433, China; Department of Materials Science, Fudan University, Shanghai 200433, China.
Center of Special Materials and Technology, Fudan University, Shanghai 200433, China.
Mater Sci Eng C Mater Biol Appl. 2014 Jun 1;39:352-8. doi: 10.1016/j.msec.2014.03.027. Epub 2014 Mar 19.
In this study, a novel hydrophilic RGO-CD-Ag hybrid with the supramolecular β-cyclodextrin (CD) as a conjugation interface was fabricated successfully by a facile in situ synthesis process. The results of several characterizations confirmed that the in situ reaction provided a straightforward approach to deposit the CD wrapped Ag nanoparticles onto the CD chemical functionalized RGO sheets through the head-to-head H-bond interactions between the linker CD molecules. Moreover, it was also found that the CD interface that existed indeed influences the structure and performances of RGO-CD-Ag nanocomposite. The analysis of the static contact angle revealed that the surface property of the hybrid could be transformed from hydrophobic to hydrophilic feature, which highly improved the aqueous dispersibility. And then, the bactericidal test of RGO-CD-Ag was demonstrated and clearly showed the strongest antibacterial activity against Gram-negative and Gram-positive bacteria among all samples. In short, this method may readily provide a new family of supramolecular based materials expected to find applications beyond the bactericidal field.
在本研究中，通过简便的原位合成工艺成功制备了一种新型的亲水性RGO-CD-Ag杂化物，其中超分子β-环糊精（CD）作为共轭界面。几种表征结果证实，原位反应提供了一种直接的方法，通过连接剂CD分子之间的头对头氢键相互作用，将CD包裹的银纳米颗粒沉积到CD化学功能化的RGO片上。此外，还发现确实存在的CD界面会影响RGO-CD-Ag纳米复合材料的结构和性能。静态接触角分析表明，杂化物的表面性质可从疏水性转变为亲水性，这极大地提高了其在水中的分散性。然后，对RGO-CD-Ag进行了杀菌测试，结果清楚地表明，在所有样品中，它对革兰氏阴性菌和革兰氏阳性菌具有最强的抗菌活性。简而言之，该方法可能很容易提供一类新的基于超分子的材料，有望在杀菌领域之外找到应用。
