Suggs Amanda, Oyetakin-White Patricia, Baron Elma D
Department of Dermatology, University Hospitals Case Medical Center 11100 Euclid Avenue, Lakeside 3500, Mailstop 5028, Cleveland, OH 44106-5028, USA.
Inflamm Allergy Drug Targets. 2014;13(3):168-76. doi: 10.2174/1871528113666140526163052.
The skin and its immune system manifest a decline in physiologic function as it undergoes aging. External insults such as ultraviolet light exposure cause inflammation, which may enhance skin aging even further leading to cancer and signs of photoaging. There is a potential role for botanicals as an adjunct modality in the prevention of skin aging. Numerous over-the-counter anti-aging products are commercially available, many of which boast unverified claims to reduce stress, inflammation and correct signs of aging. In this article we reviewed the scientific literature for data on frequently published "anti-inflammaging" additives such as vitamins A, C and E and green tea. We also analyzed the evidence available on five promising ingredients commonly found in anti-aging products, namely, argan oil, rosemary, pomegranate, Coenzyme Q10, and Coffeeberry. Though there may be an increasing amount of scientific data on a few of these novel botanicals, in general, there remains a lack of clinical data to support the anti-aging claims made.
随着年龄增长，皮肤及其免疫系统的生理功能会出现衰退。诸如紫外线照射等外部损伤会引发炎症，这可能会进一步加剧皮肤衰老，甚至导致癌症和光老化迹象。植物提取物在预防皮肤衰老方面可能具有辅助作用。市面上有许多非处方抗衰产品，其中许多产品宣称具有减轻压力、抗炎和改善衰老迹象等未经证实的功效。在本文中，我们查阅了科学文献，以获取有关经常发表的“抗炎症衰老”添加剂的数据，如维生素A、C和E以及绿茶。我们还分析了抗衰产品中常见的五种有前景的成分的现有证据，即阿甘油、迷迭香、石榴、辅酶Q10和咖啡果。尽管关于这些新型植物提取物中的一些可能有越来越多的科学数据，但总体而言，仍然缺乏支持其抗衰宣称的临床数据。
