Harris M M, Lawson D, Cooper C M, Ellis J
Department of Anesthesiology, University of Virginia Medical Center, Charlottesville 22908.
Reg Anesth. 1989 Jan-Feb;14(1):13-8.
The effectiveness of intravenous meperidine and warm local anesthetic for prevention of postanesthetic shivering was evaluated in urology patients undergoing epidural blockade for extracorporeal shockwave lithotripsy. When administered before the blockade, meperidine, 12.5 mg or 25 mg, was not significantly better than saline placebo for preventing postepidural shivering. Changes in the concentrations of catecholamines or lidocaine did not result in differences between patients who shivered and those who did not shiver. In a second experiment, patients receiving body-temperature or room-temperature epidural lidocaine did not differ with respect to the incidence of postanesthetic shivering, onset of sensory blockade, or core temperature during a 30-minute observation period. The authors concluded that neither meperidine, in doses employed, nor body-temperature lidocaine prevents shivering after epidural blockade. This shivering appears to be different from that observed during emergence from general anesthesia.
在接受硬膜外阻滞以进行体外冲击波碎石术的泌尿外科患者中，评估了静脉注射哌替啶和温热局部麻醉剂预防麻醉后寒战的效果。在阻滞前给药时，12.5毫克或25毫克的哌替啶在预防硬膜外麻醉后寒战方面并不比生理盐水安慰剂显著更好。儿茶酚胺或利多卡因浓度的变化并未导致寒战患者与未寒战患者之间出现差异。在第二项实验中，接受体温或室温硬膜外利多卡因的患者在30分钟观察期内的麻醉后寒战发生率、感觉阻滞开始时间或核心体温方面并无差异。作者得出结论，所用剂量的哌替啶和体温利多卡因均不能预防硬膜外阻滞后的寒战。这种寒战似乎与全身麻醉苏醒期间观察到的寒战不同。
