恒河猴（猕猴）白质扩散张量成像（DTI）的参数比较
Parameter comparison of white matter diffusion tensor imaging (DTI) in rhesus macaques (Macaca mulatta).
作者信息
Mo Yin, Chao Fang, Song Ming, Liu Ci-Rong, Liu Hui-Lang, Qian Xi-Ying, Zhao Xu-Dong
机构信息
Department of Medical Imaging, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
出版信息
Dongwuxue Yanjiu. 2014 May;35(3):182-5. doi: 10.11813/j.issn.0254-5853.2014.3.182.
In this study, we analyzed diffusion tensor imaging (DTI) results of brain white matter in rhesus macaques (Macaca mulatta) with four different parameter settings and found that the sequence A (b=1 000 s/mm(2), spatial resolution=1.25 mm×1.25 mm× 1.25 mm, numbers of direction=33, NSA=3) and B (b=800 s/mm(2), spatial resolution=1.25 mm×1.25 mm×1.25 mm, numbers of direction=33, NSA=3) could accurately track coarse fibers. The fractional anisotropy (FA) derived from sequence C (b=1 000s/mm(2), spatial resolution=0.55 mm×0.55 mm×2.5 mm, direction number=33, NSA=3) was too fuzzy to be used in tracking white matter fibers. By comparison, the high resolution and the FA with high contrast of gray matter and white matter derived from sequence D (b=800 s/mm(2), spatial resolution=1.0 mm×1.0 mm ×1.0 mm, numbers of direction=33, NSA=3) qualified in its application in tracking both thick and thin fibers, making it an optimal DTI setting for rhesus macaques.
在本研究中，我们分析了恒河猴（猕猴属）脑白质在四种不同参数设置下的扩散张量成像（DTI）结果，发现序列A（b = 1000 s/mm²，空间分辨率 = 1.25 mm×1.25 mm×1.25 mm，方向数 = 33，激励次数 = 3）和序列B（b = 800 s/mm²，空间分辨率 = 1.25 mm×1.25 mm×1.25 mm，方向数 = 33，激励次数 = 3）能够准确追踪粗纤维。序列C（b = 1000 s/mm²，空间分辨率 = 0.55 mm×0.55 mm×2.5 mm，方向数 = 33，激励次数 = 3）得出的分数各向异性（FA）过于模糊，无法用于追踪白质纤维。相比之下，序列D（b = 800 s/mm²，空间分辨率 = 1.0 mm×1.0 mm×1.0 mm，方向数 = 33，激励次数 = 3）具有高分辨率以及灰质和白质对比度高的FA，适用于追踪粗细纤维，使其成为恒河猴DTI的最佳设置。
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