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脑电图与阿尔茨海默病:临床与研究方法

Electroencephalogram and Alzheimer's disease: clinical and research approaches.

作者信息

Tsolaki Anthoula, Kazis Dimitrios, Kompatsiaris Ioannis, Kosmidou Vasiliki, Tsolaki Magda

机构信息

Medical Physics Laboratory, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

3rd Department of Neurology, Aristotle University of Thessaloniki, Exochi, 57010 Thessaloniki, Greece.

出版信息

Int J Alzheimers Dis. 2014;2014:349249. doi: 10.1155/2014/349249. Epub 2014 Apr 24.

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by cognitive deficits, problems in activities of daily living, and behavioral disturbances. Electroencephalogram (EEG) has been demonstrated as a reliable tool in dementia research and diagnosis. The application of EEG in AD has a wide range of interest. EEG contributes to the differential diagnosis and the prognosis of the disease progression. Additionally such recordings can add important information related to the drug effectiveness. This review is prepared to form a knowledge platform for the project entitled "Cognitive Signal Processing Lab," which is in progress in Information Technology Institute in Thessaloniki. The team tried to focus on the main research fields of AD via EEG and recent published studies.

摘要

阿尔茨海默病(AD)是一种神经退行性疾病,其特征为认知缺陷、日常生活活动问题及行为障碍。脑电图(EEG)已被证明是痴呆症研究和诊断中的一种可靠工具。EEG在AD中的应用受到广泛关注。EEG有助于疾病的鉴别诊断和病情进展的预后评估。此外,此类记录可提供与药物疗效相关的重要信息。本综述旨在为塞萨洛尼基信息技术研究所正在进行的“认知信号处理实验室”项目构建一个知识平台。该团队试图通过EEG及近期发表的研究聚焦于AD的主要研究领域。

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