Livas Rodríguez S, Triana Saldaña H G, Ploneda González C
Ginecol Obstet Mex. 1989 Jul;57:182-4.
Systemic Lupus Erythematosus in an autoimmune disease of unknown etiology, which is seen more frequently in women than in men, especially in the reproductive age range, and which when associated with pregnancy may be lethal if the diagnosis is not made opportunely or treatment is inadequate. This report presents two cases of systemic lupus erythematosus during pregnancy one of which was diagnosed during the first trimester and which, with good prenatal care, respond well to treatment with prednisone and remained inactive during the pregnancy resulting in a favorable outcome. The second case was diagnosed in the second trimester with select manifestations of the disease activity which evolved poorly resulting in a fatal outcome for mother and fetus.
系统性红斑狼疮是一种病因不明的自身免疫性疾病,女性比男性更常见,尤其是在育龄期,若与妊娠相关,若诊断不及时或治疗不当可能会致命。本报告介绍了两例妊娠期系统性红斑狼疮病例,其中一例在孕早期被诊断,通过良好的产前护理,对泼尼松治疗反应良好,孕期病情保持稳定,结果良好。第二例在孕中期被诊断,有疾病活动的特定表现,病情进展不佳,导致母婴死亡。