Bracha H S
Neuropsychiatric Special Evaluation Unit, VA Medical Center, North Little Rock, AR 72114.
Schizophr Res. 1989 Jul-Oct;2(4-5):317-24. doi: 10.1016/0920-9964(89)90022-4.
This selective review argues that a small subgroup among the patients meeting DSM-III-R criteria for schizophrenia appears to have an underlying right striatal hyper-dopaminergia. The subgroup is distinguished by a group of objective signs including: (1) asymmetric, usually right-sided, neuroleptic induced parkinsonian side effects; (2) asymmetric, usually left-sided, tardive dyskinesia; (3) a subclinical tendency to turn toward the left; (4) a subclinical right hemi-space sensory neglect; and (5) dopamine receptor densities greater in the right striatum than in the left.
