食管癌：分期系统以及分期与治疗指南。
Esophageal cancer: staging system and guidelines for staging and treatment.
作者信息
Berry Mark F
机构信息
Department of Surgery, Division of Thoracic Surgery, Duke University Medical Center, Durham, North Carolina, USA.
出版信息
J Thorac Dis. 2014 May;6 Suppl 3(Suppl 3):S289-97. doi: 10.3978/j.issn.2072-1439.2014.03.11.
Abstract
Survival of esophageal cancer is improving but remains poor. Esophageal cancer stage is based on depth of tumor invasion, involvement of regional lymph nodes, and the presence or absence of metastatic disease. Appropriate work-up is critical to identify accurate pre-treatment staging so that both under-treatment and unnecessary treatment is avoided. Treatment strategy should follow guideline recommendations, and generally should be developed after multidisciplinary evaluation.
摘要
食管癌的生存率正在提高，但仍然很低。食管癌分期基于肿瘤浸润深度、区域淋巴结受累情况以及是否存在转移性疾病。适当的检查对于确定准确的治疗前分期至关重要，这样可以避免治疗不足和不必要的治疗。治疗策略应遵循指南建议，并且通常应在多学科评估后制定。
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J Thorac Oncol. 2013 Jun;8(6):796-802. doi: 10.1097/JTO.0b013e3182897bf1.
2
Trends and outcomes in the use of surgery and radiation for the treatment of locally advanced esophageal cancer: a propensity score adjusted analysis of the surveillance, epidemiology, and end results registry from 1998 to 2008.手术和放疗用于治疗局部晚期食管癌的趋势及疗效：对1998年至2008年监测、流行病学和最终结果登记处数据的倾向评分调整分析
Dis Esophagus. 2014 Sep-Oct;27(7):662-9. doi: 10.1111/dote.12123. Epub 2013 Aug 13.
3
Complete clinical response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic oesophagus: is surgery always necessary?新辅助放化疗后胸段食管鳞癌完全临床缓解：是否仍需手术？
J Gastrointest Surg. 2013 Aug;17(8):1375-81. doi: 10.1007/s11605-013-2269-3.
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Ann Thorac Surg. 2013 Jul;96(1):346-56. doi: 10.1016/j.athoracsur.2013.02.069. Epub 2013 Jun 7.
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9
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