患有非增殖性、增殖性视网膜病变及无视网膜病变的糖尿病患者的血清同型半胱氨酸水平。
Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy.
作者信息
Malaguarnera Giulia, Gagliano Caterina, Giordano Maria, Salomone Salvatore, Vacante Marco, Bucolo Claudio, Caraci Filippo, Reibaldi Michele, Drago Filippo, Avitabile Teresio, Motta Massimo
机构信息
International Ph.D. programme in Neuropharmacology, University of Catania, 95123 Catania, Italy.
Department of Ophthalmology, University of Catania, 95123 Catania, Italy.
出版信息
Biomed Res Int. 2014;2014:191497. doi: 10.1155/2014/191497. Epub 2014 Apr 28.
Abstract
Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.
摘要
同型半胱氨酸与细胞外基质变化有关。糖尿病视网膜病变是糖尿病的一种神经血管并发症，是全球在职成年人视力丧失的主要原因。在本研究中，我们通过分析63例2型非增殖性糖尿病视网膜病变（NPDR）患者、62例增殖性糖尿病视网膜病变（PDR）患者、50例作为对照组的健康受试者以及75例随机选取患者的血浆同型半胱氨酸水平，评估同型半胱氨酸在糖尿病视网膜病变中的作用。
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