Stadler P, van Amstel S R
Departement Geneeskunde, Fakultet Veeartsenykunde, Universiteit van Pretoria, Repubilek van Suid-Afrika.
J S Afr Vet Assoc. 1989 Dec;60(4):198-200.
The results of a study conducted to determine the clinical changes in 4 experimentally-induced cases of endotoxaemia in the horse are reported on. Endotoxaemia was induced by injecting commercially available E. coli 055:B5 lipopolysaccharide intravenously at a dose of 1 microgram kg-1. The parameters that were monitored include general behaviour, rectal temperature, heart rate, respiratory rate and quality, pulse quality, mucous membrane colour, capillary refill time, appearance of the faeces and the presence of laminitis. Increases in rectal temperature, respiratory and heart rate, capillary refill time, the development of a bounding peripheral pulse, dyspnoea and congestion of mucous membranes, decrease in faecal consistency and behavioural changes were recorded.
本文报告了一项旨在确定4例实验诱导的马内毒素血症临床变化的研究结果。通过静脉注射剂量为1微克/千克的市售大肠杆菌055:B5脂多糖诱导内毒素血症。监测的参数包括一般行为、直肠温度、心率、呼吸频率和质量、脉搏质量、黏膜颜色、毛细血管再充盈时间、粪便外观以及蹄叶炎的存在情况。记录到直肠温度、呼吸和心率升高，毛细血管再充盈时间延长，外周脉搏洪大，呼吸困难和黏膜充血，粪便稠度降低以及行为改变。
