Zandbergen J, Pols H, De Loof C, Lousberg H, Griez E
State University of Limburg, Department of Clinical Psychiatry, Maastricht, The Netherlands.
Hillside J Clin Psychiatry. 1989;11(2):185-97.
Naturally occurring panic attacks and various interventions which trigger anxiety in panic patients are accompanied by disturbances in the acid-base balance. Carbon dioxide appears to play an important role in many experimental panic provoking conditions. The influence of respiratory and metabolic pH disturbances on cerebral physiology is discussed and speculations are made about the possible mechanisms underlying CO2-induced anxiety in panic disorder.
自然发生的惊恐发作以及引发惊恐症患者焦虑的各种干预措施都伴随着酸碱平衡的紊乱。在许多实验性惊恐诱发条件下，二氧化碳似乎起着重要作用。本文讨论了呼吸性和代谢性pH紊乱对大脑生理的影响，并对惊恐障碍中二氧化碳诱发焦虑的可能机制进行了推测。
