偏头痛患者的性功能与偏头痛相关残疾、抑郁和焦虑的关系。
The relation of sexual function to migraine-related disability, depression and anxiety in patients with migraine.
机构信息
Department of Neurology, Acıbadem University School of Medicine, Acıbadem Maslak Hospital, Büyükdere Caddesi, No:40, Maslak/Sarıyer, 34457 Istanbul, Turkey.
出版信息
J Headache Pain. 2014 May 27;15(1):32. doi: 10.1186/1129-2377-15-32.
BACKGROUND
Depression and anxiety are two phenomena that affect quality of life as well as sexual function. Depression and anxiety levels are reported to be high in migraine sufferers. We aimed to understand whether sexual function in women with migraine was associated to migraine-related disability and frequency of migraine attacks, and whether this relationship was modulated by depressive and anxiety symptoms.
METHODS
As migraine is more commonly seen in females, a total of 50 women with migraine were included. The diagnosis of migraine with or without aura was confirmed by two specialists in Neurology, according to the second edition of International Headache Society (IHS) International Classification of Headache Disorders (ICHD-II) in 2004. Migraine disability assessment scale score, female sexual function index scores, Beck depression inventory score and Beck anxiety inventory scores.
RESULTS
Mean MIDAS score was 19.3 ± 12.8, and mean number of migraine attacks per month were 4.3 ± 2.7. Mean Female Sexual Function Index score was 20.9 ± 5.9 and 90% of patients had sexual dysfunction. Sexual dysfunction was not related to MIDAS score or frequency and severity of attacks. No relationship between sexual function and anxiety was found, whereas severity of depressive symptoms was closely related to sexual function. Depressive symptoms affected all dimensions of sexual function, except for pain.
CONCLUSION
Sexual dysfunction seemed to be very common in our patients with migraine, while not related to migraine related disability, frequency of attacks and migraine severity or anxiety. The most important factor that predicted sexual function was depression, which was also independent of disease severity and migraine related disability. While future larger scale studies are needed to clarify the exact relationship, depressive and sexual problems should be properly addressed in all patients with migraine, regardless of disease severity or disability.
背景
抑郁和焦虑是两种影响生活质量和性功能的现象。偏头痛患者的抑郁和焦虑水平报告较高。我们旨在了解偏头痛女性的性功能是否与偏头痛相关残疾和偏头痛发作频率有关，以及这种关系是否受抑郁和焦虑症状的调节。
方法
由于偏头痛更常见于女性，共纳入 50 名偏头痛女性。根据 2004 年国际头痛协会（IHS）第二次国际头痛疾病分类（ICHD-II），两位神经病学专家确诊偏头痛伴或不伴先兆。偏头痛残疾评估量表评分、女性性功能指数评分、贝克抑郁量表评分和贝克焦虑量表评分。
结果
平均 MIDAS 评分为 19.3±12.8，每月偏头痛发作平均次数为 4.3±2.7。平均女性性功能指数评分为 20.9±5.9，90%的患者存在性功能障碍。性功能障碍与 MIDAS 评分或发作频率和严重程度无关。未发现性功能与焦虑之间存在关系，而抑郁症状严重程度与性功能密切相关。抑郁症状影响性功能的所有维度，除疼痛外。
结论
在我们的偏头痛患者中，性功能障碍似乎非常常见，与偏头痛相关残疾、发作频率和偏头痛严重程度或焦虑无关。预测性功能的最重要因素是抑郁，这也与疾病严重程度和偏头痛相关残疾无关。虽然需要未来更大规模的研究来阐明确切的关系，但无论疾病严重程度或残疾如何，都应妥善解决抑郁和性功能问题所有偏头痛患者。
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