Ezeh Osita Kingsley, Agho Kingsley Emwinyore, Dibley Michael John, Hall John, Page Andrew Nicholas
School of Science and Health, University of Western Sydney, Locked Bag 1797, Penrith, New South Wales (NSW) 2571, Australia.
BMC Public Health. 2014 May 29;14:521. doi: 10.1186/1471-2458-14-521.
Nigeria continues to have one of the highest rates of neonatal deaths in Africa. This study aimed to identify risk factors associated with neonatal death in Nigeria using the 2008 Nigeria Demographic and Health Survey (NDHS).
Neonatal deaths of all singleton live-born infants between 2003 and 2008 were extracted from the 2008 NDHS. The 2008 NDHS was a multi-stage cluster sample survey of 36,298 households. Of these households, survival information of 27,147 singleton live-borns was obtained, including 996 cases of neonatal mortality. The risk of death was adjusted for confounders relating to individual, household, and community level factors using Cox regression.
Multivariable analyses indicated that a higher birth order of newborns with a short birth interval ≤ 2 years (hazard ratio [HR] = 2.19, confidence interval [CI]: 1.68-2.84) and newborns with a higher birth order with a longer birth interval > 2 years (HR = 1.36, CI: 1.05-1.78) were significantly associated with neonatal mortality. Other significant factors that affected neonatal deaths included neonates born to mothers younger than 20 years (HR = 4.07, CI: 2.83-5.86), neonates born to mothers residing in rural areas compared with urban residents (HR = 1.26, CI: 1.03-1.55), male neonates (HR = 1.30, CI: 1.12-1.53), mothers who perceived their neonate's body size to be smaller than the average size (HR = 2.10, CI: 1.77-2.50), and mothers who delivered their neonates by caesarean section (HR = 2.80, CI: 1.84-4.25).
Our study suggests that the Nigerian government needs to invest more in the healthcare system to ensure quality care for women and newborns. Community-based intervention is also required and should focus on child spacing, childbearing at a younger age, and poverty eradication programs, particularly in rural areas, to reduce avoidable neonatal deaths in Nigeria.
尼日利亚仍然是非洲新生儿死亡率最高的国家之一。本研究旨在利用2008年尼日利亚人口与健康调查(NDHS)确定与尼日利亚新生儿死亡相关的风险因素。
从2008年NDHS中提取2003年至2008年期间所有单胎活产婴儿的新生儿死亡情况。2008年NDHS是对36298户家庭进行的多阶段整群抽样调查。在这些家庭中,获得了27147名单胎活产儿的生存信息,包括996例新生儿死亡病例。使用Cox回归对与个人、家庭和社区层面因素相关的混杂因素进行死亡风险调整。
多变量分析表明,出生间隔较短(≤2年)且出生顺序较高的新生儿(风险比[HR]=2.19,置信区间[CI]:1.68 - 2.84)以及出生间隔较长(>2年)且出生顺序较高的新生儿(HR = 1.36,CI:1.05 - 1.78)与新生儿死亡率显著相关。其他影响新生儿死亡的重要因素包括母亲年龄小于20岁的新生儿(HR = 4.07,CI:2.83 - 5.86)、与城市居民相比居住在农村地区的母亲所生的新生儿(HR = 1.26,CI:1.03 - 1.55)、男性新生儿(HR = 1.30,CI:1.12 - 1.53)、母亲认为其新生儿体型小于平均体型的(HR = 2.10,CI:1.77 - 2.50)以及通过剖宫产分娩的母亲所生的新生儿(HR = 2.80,CI:1.84 - 4.25)。
我们的研究表明,尼日利亚政府需要在医疗保健系统上投入更多资金,以确保为妇女和新生儿提供优质护理。还需要开展基于社区的干预措施,应侧重于生育间隔、晚婚晚育以及消除贫困项目,特别是在农村地区,以减少尼日利亚可避免的新生儿死亡。