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尼日利亚新生儿期后、婴儿、儿童及5岁以下儿童死亡的风险因素:一项汇总横断面分析

Risk factors for postneonatal, infant, child and under-5 mortality in Nigeria: a pooled cross-sectional analysis.

作者信息

Ezeh Osita Kingsley, Agho Kingsley Emwinyore, Dibley Michael John, Hall John Joseph, Page Andrew Nicolas

机构信息

School of Medicine, University of Western Sydney, Campbelltown, New South Wales, Australia.

School of Science and Health, University of Western Sydney, Campbelltown, New South Wales, Australia.

出版信息

BMJ Open. 2015 Mar 27;5(3):e006779. doi: 10.1136/bmjopen-2014-006779.

Abstract

OBJECTIVES

To identify common factors associated with post-neonatal, infant, child and under-5 mortality in Nigeria.

DESIGN, SETTING AND PARTICIPANTS: A cross-sectional data of three Nigeria Demographic and Health Surveys (NDHS) for the years 2003, 2008 and 2013 were used. A multistage, stratified, cluster random sampling method was used to gather information on 63,844 singleton live-born infants of the most recent birth of a mother within a 5-year period before each survey was examined using cox regression models.

MAIN OUTCOME MEASURES

Postneonatal mortality (death between 1 and 11 months), infant mortality (death between birth and 11 months), child mortality (death between 12 and 59 months) and under-5 mortality (death between birth and 59 months).

RESULTS

Multivariable analyses indicated that children born to mothers with no formal education was significantly associated with mortality across all four age ranges (adjusted HR=1.30, 95% CI 1.01 to 1.66 for postneonatal; HR=1.38, 95% CI 1.11 to 1.84 for infant; HR=2.13, 95% CI 1.56 to 2.89 for child; HR=1.19, 95% CI 1.02 to 1.41 for under-5). Other significant factors included living in rural areas (HR=1.48, 95% CI 1.16 to 1.89 for postneonatal; HR=1.23, 95% CI 1.03 to 1.47 for infant; HR=1.52, 95% CI 1.16 to 1.99 for child; HR=1.29, 95% CI 1.11 to 1.50 for under-5), and poor households (HR=2.47, 95% CI 1.76 to 3.47 for postneonatal; HR=1.40, 95% CI 1.10 to 1.78 for infant; HR=1.72, 95% CI 1.19 to 2.49 for child; HR=1.43, 95% CI 1.17 to 1.76 for under-5).

CONCLUSIONS

This study found that no formal education, poor households and living in rural areas increased the risk of postneonatal, infant, child and under-5 mortality among Nigerian children. Community-based interventions for reducing under-5 deaths are needed and should target children born to mothers of low socioeconomic status.

摘要

目标

确定与尼日利亚新生儿后期、婴儿、儿童及5岁以下儿童死亡率相关的常见因素。

设计、背景与参与者:使用了2003年、2008年和2013年三次尼日利亚人口与健康调查(NDHS)的横断面数据。采用多阶段、分层、整群随机抽样方法,收集了在每次调查前5年内母亲最近一次生育的63,844名单胎活产婴儿的信息,并使用考克斯回归模型进行分析。

主要观察指标

新生儿后期死亡率(1至11个月之间死亡)、婴儿死亡率(出生至11个月之间死亡)、儿童死亡率(12至59个月之间死亡)及5岁以下儿童死亡率(出生至59个月之间死亡)。

结果

多变量分析表明,母亲未接受过正规教育的儿童在所有四个年龄范围内的死亡率均显著升高(新生儿后期调整后风险比[HR]=1.30,95%置信区间[CI]为1.01至1.66;婴儿HR=1.38,95%CI为1.11至1.84;儿童HR=2.13,95%CI为1.56至2.89;5岁以下儿童HR=1.19,95%CI为1.02至1.41)。其他显著因素包括生活在农村地区(新生儿后期HR=1.48,95%CI为1.16至1.89;婴儿HR=1.23,95%CI为1.03至1.47;儿童HR=1.52,95%CI为1.16至1.99;5岁以下儿童HR=1.29,95%CI为1.11至1.50)以及贫困家庭(新生儿后期HR=2.47,95%CI为1.76至3.47;婴儿HR=1.40,95%CI为1.10至1.78;儿童HR=1.72,95%CI为1.19至2.49;5岁以下儿童HR=1.43,�5%CI为1.17至1.76)。

结论

本研究发现,未接受正规教育、贫困家庭以及生活在农村地区会增加尼日利亚儿童的新生儿后期、婴儿、儿童及5岁以下儿童死亡率。需要开展基于社区的干预措施以降低5岁以下儿童死亡,且应针对社会经济地位低下母亲所生的儿童。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7284/4386230/7312e1a8d63f/bmjopen2014006779f01.jpg

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