儿童侵袭性念珠菌病中的念珠菌菌种鉴定、抗真菌治疗及不良事件：一项前瞻性多国研究中441例感染的结果
Candida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study.
作者信息
Palazzi Debra L, Arrieta Antonio, Castagnola Elio, Halasa Natasha, Hubbard Sydney, Brozovich Ava A, Fisher Brian T, Steinbach William J
机构信息
From the *Baylor College of Medicine and Texas Children's Hospital, Houston, TX; †Children's Hospital of Orange County, Orange, CA; ‡Istituto Giannina Gaslini, Genova, Italy; §Monroe Carell Jr. Children's Hospital at Vanderbilt University, Nashville, TN; ¶Children's Hospital of Philadelphia, Philadelphia, PA; and ‖Duke University, Durham, NC.
出版信息
Pediatr Infect Dis J. 2014 Dec;33(12):1294-6. doi: 10.1097/INF.0000000000000431.
A multi-national prospective study of pediatric patients with invasive candidiasis between August 2007 and September 2012 was performed and included 441 infections. Variation in infecting Candida species and antifungals used was noted between US and non-US sites. Antifungal-associated adverse events were most common with polyene use.
2007年8月至2012年9月间，对患有侵袭性念珠菌病的儿科患者进行了一项多国前瞻性研究，共纳入441例感染病例。研究发现，美国和非美国地区在感染念珠菌种类及使用的抗真菌药物方面存在差异。使用多烯类抗真菌药物时，与抗真菌药物相关的不良事件最为常见。
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