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Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study).比较英夫利昔单抗和大剂量静脉类固醇诱导缓解，然后进行达标治疗：新发病、未经治疗的类风湿关节炎的双盲、随机、对照试验（IDEA 研究）。
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风湿性疾病的神经系统并发症。

Neurologic complications of rheumatic disease.

作者信息

Goldstein Jonathan M

出版信息

Continuum (Minneap Minn). 2014 Jun;20(3 Neurology of Systemic Disease):657-69. doi: 10.1212/01.CON.0000450972.06947.37.

DOI:10.1212/01.CON.0000450972.06947.37
PMID:24893240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10563955/
Abstract

PURPOSE OF REVIEW

This article discusses the specific neurologic issues that arise in patients with rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus, and Sjögren syndrome. Diagnosis and management are discussed.

RECENT FINDINGS

Advances include advanced imaging, serologic and CSF markers, and targeted immune-modulating therapies. The use of these modalities are discussed in detail.

SUMMARY

Rheumatic disorders are quite common and can result in disabling but many times treatable neurologic sequelae. The key is early diagnosis and management. Awareness of the common presentations and current modalities of diagnosis and treatment is critical to improved outcomes.

摘要

综述目的

本文讨论了类风湿关节炎、系统性红斑狼疮和干燥综合征等风湿性疾病患者出现的特定神经问题。探讨了诊断和管理方法。

最新发现

进展包括先进的影像学检查、血清学和脑脊液标志物以及靶向免疫调节疗法。详细讨论了这些方法的应用。

总结

风湿性疾病相当常见，可导致致残但很多时候可治疗的神经后遗症。关键是早期诊断和管理。了解常见表现以及当前的诊断和治疗方法对于改善预后至关重要。