Dabrowski R, Szczepanowska A
Pol J Occup Med. 1989;2(3):279-85.
The effects of exogenous histamine (Hi) and endogenous Hi (brought about by treatment with 48/80*] on the levels of collagen and glycosaminoglycans (GAG) in the skin of both newborns and their mothers were studied. Exogenous Hi injected into the mothers somewhat increased Hi level in the skin of the newborns and did not change the levels of collagen and GAG. 48/80 administered to the mothers resulted in a decrease of Hi in their skin and elevated it in skin of the newborns. The levels of collagen and GAG in the skin of the mothers were lower after 48/80 than in the control. However, 48/80 injected into the mothers resulted in an increase of collagen and GAG in skin of the newborns.
研究了外源性组胺(Hi)和内源性Hi(通过48/80处理产生)对新生儿及其母亲皮肤中胶原蛋白和糖胺聚糖(GAG)水平的影响。给母亲注射外源性Hi会使新生儿皮肤中的Hi水平略有增加,但不会改变胶原蛋白和GAG的水平。给母亲注射48/80会导致其皮肤中Hi水平降低,而新生儿皮肤中Hi水平升高。48/80处理后,母亲皮肤中胶原蛋白和GAG的水平低于对照组。然而,给母亲注射48/80会导致新生儿皮肤中胶原蛋白和GAG增加。