Feng Shuang, Liu Dajiang, Zhan Xiaowei, Wing Mary Kate, Abecasis Gonçalo R
Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
Bioinformatics. 2014 Oct;30(19):2828-9. doi: 10.1093/bioinformatics/btu367. Epub 2014 Jun 3.
RAREMETAL is a computationally efficient tool for meta-analysis of rare variants genotyped using sequencing or arrays. RAREMETAL facilitates analyses of individual studies, accommodates a variety of input file formats, handles related and unrelated individuals, executes both single variant and burden tests and performs conditional association analyses.
http://genome.sph.umich.edu/wiki/RAREMETAL for executables, source code, documentation and tutorial.
RAREMETAL是一种计算效率高的工具，用于对使用测序或阵列进行基因分型的罕见变异进行荟萃分析。RAREMETAL有助于对个体研究进行分析，支持多种输入文件格式，处理相关和不相关个体，执行单变异和负担检验，并进行条件关联分析。
可从http://genome.sph.umich.edu/wiki/RAREMETAL获取可执行文件、源代码、文档和教程。
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