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[德国复苏登记处:科学与复苏研究]

[German resuscitation registry : science and resuscitation research].

作者信息

Gräsner J-T, Seewald S, Bohn A, Fischer M, Messelken M, Jantzen T, Wnent J

机构信息

Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schwanenweg 21, 24105, Kiel, Deutschland,

出版信息

Anaesthesist. 2014 Jun;63(6):470-6. doi: 10.1007/s00101-014-2324-9.

Abstract

Sudden death due to cardiac arrest represents one of the greatest challenges facing modern medicine, not only because of the massive number of cases involved but also because of its tremendous social and economic impact. For many years, the magic figure of 1 per 1000 inhabitants per year was generally accepted as an estimate of the annual incidence of sudden death in the industrialized world, with a survival rate of 6 %. This estimate was based on large numbers of published reports of local, regional, national and multinational experience in the management of cardiac arrest. Measuring the global incidence of cardiac arrest is challenging as many different definitions of patient populations are used. Randomized controlled trials (RCT) provide insights into the value of specific treatments or treatment strategies in a well-defined section of a population. Registries do not compete with clinical studies, but represent a useful supplement to them. Surveys and registries provide insights into the ways in which scientific findings and guidelines are being implemented in clinical practice. However, as with clinical studies, comprehensive preparations are needed in order to establish a registry. This is all the more decisive because not all of the questions that may arise are known at the time when the registry is established. The German resuscitation registry started in May 2007 and currently more than 230 paramedic services and hospitals take part. More than 45,000 cases of out-of-hospital cardiac arrest and in-hospital cardiac arrest are included. With this background the German resuscitation registry is one of the largest databases in emergency medicine in Germany. After 5 years of running the preclinical care dataset was revised in 2012. Data variables that reflect current or new treatment were added to the registry. The postresuscitation basic care and telephone cardiopulmonary resuscitation (CPR) datasets were developed in 2012 and 2013 as well. The German resuscitation registry is an instrument of quality management and a research network. The registry documents the course in patients who have undergone resuscitation at the time points of first aid, further management and long-term outcome and it can therefore provide a complete presentation of the procedures carried out and the quality of the outcomes. In addition, important scientific questions can be answered from the database. For example, a score for benchmarking the outcome quality after out-of-hospital resuscitation, known as the return of spontaneous circulation (ROSC) after cardiac arrest (RACA) score, has been developed. The registry is available for all emergency medical services (EMS) and hospitals in Germany and other German-speaking countries.

摘要

心脏骤停导致的猝死是现代医学面临的最大挑战之一,这不仅是因为涉及的病例数量众多,还因其巨大的社会和经济影响。多年来,工业化国家每年每1000名居民中有1例猝死的神奇数字被普遍视为猝死年发病率的估计值,生存率为6%。这一估计基于大量已发表的关于心脏骤停管理的地方、区域、国家和跨国经验的报告。由于使用了许多不同的患者群体定义,测量全球心脏骤停发病率具有挑战性。随机对照试验(RCT)能深入了解特定治疗或治疗策略在明确界定的人群中的价值。登记处并非与临床研究竞争,而是对其有用的补充。调查和登记处能深入了解科学发现和指南在临床实践中的实施方式。然而,与临床研究一样,建立登记处需要全面准备。这一点尤为关键,因为在建立登记处时并非所有可能出现的问题都已知。德国复苏登记处始于2007年5月,目前有230多家护理人员服务机构和医院参与。登记了超过45000例院外心脏骤停和院内心脏骤停病例。在此背景下,德国复苏登记处是德国急诊医学领域最大的数据库之一。运行5年后,2012年对临床前护理数据集进行了修订。反映当前或新治疗方法的数据变量被添加到登记处。复苏后基本护理和电话心肺复苏(CPR)数据集也分别于2012年和2013年制定。德国复苏登记处是质量管理工具和研究网络。该登记处记录了患者在急救、进一步治疗和长期结果等时间点的复苏过程,因此可以完整呈现所实施的程序和结果质量。此外,重要的科学问题可以从数据库中得到解答。例如,已经开发出一种用于衡量院外复苏后结果质量的评分,即心脏骤停后自主循环恢复(ROSC)评分(RACA评分)。该登记处可供德国和其他德语国家的所有紧急医疗服务(EMS)机构和医院使用。

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