Department of Chemistry, Western Kentucky University, Bowling Green, KY, 42101.
Front Biosci (Landmark Ed). 2014 Jun 1;19(8):1320-44. doi: 10.2741/4284.
Colloidal gold is very attractive for several applications in biotechnology because of its unique physical and chemical properties. Many different synthesis methods have been developed to generate gold nanoparticles (AuNPs). Here, we will introduce these methods and discuss the differences between fabrication techniques. We will also discuss ecofriendly synthesis methods being developed to efficiently generate AuNPs without the use of toxic substrates. Finally, we will discuss the medical applications for AuNPs by highlighting the potential use of intact or functionalized AuNPs in combating bacterial infections.
胶体金因其独特的物理和化学性质，在生物技术的多个应用领域都极具吸引力。目前已经开发出许多不同的合成方法来制备金纳米粒子（AuNPs）。在这里，我们将介绍这些方法，并讨论它们之间的差异。我们还将讨论正在开发的环保型合成方法，这些方法可以在不使用有毒底物的情况下高效地生成 AuNPs。最后，我们将通过突出完整或功能化的 AuNPs 在对抗细菌感染方面的潜在用途，来讨论 AuNPs 的医学应用。
