18F-FDG PET/CT诊断急性Q热肝炎1例
A Case of Acute Q Fever Hepatitis Diagnosed by F-18 FDG PET/CT.
作者信息
Oh Minyoung, Baek Sora, Lee Sang-Oh, Yu Eunsil, Ryu Jin-Sook
机构信息
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 86, Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736 Republic of Korea.
Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150, Sungan-ro, Kangdong-gu, Seoul, 134-701 Republic of Korea.
出版信息
Nucl Med Mol Imaging. 2012 Jun;46(2):125-8. doi: 10.1007/s13139-012-0130-3. Epub 2012 Mar 27.
A 53-year-old man with fever of unknown origin underwent F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) as a workup for a fever of unknown origin. On presentation, he complained of fever, chills, and myalgia. The F-18 FDG PET/CT scan showed diffusely increased uptake of the liver with mild hepatomegaly. A liver biopsy then revealed fibrin-ring granulomas typically seen in Q fever. The patient was later serologically diagnosed as having acute Q fever as the titers for C. burnetii IgM and IgG were 64:1 and 16:1, respectively. He recovered completely following administration of doxycycline. This indicates that F-18 FDG PET/CT may be helpful for identifying hepatic involvement in Q fever as a cause of fever of unknown origin.
一名53岁不明原因发热的男性接受了F-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-18 FDG PET/CT），作为不明原因发热的检查手段。就诊时，他主诉发热、寒战和肌痛。F-18 FDG PET/CT扫描显示肝脏弥漫性摄取增加，伴有轻度肝肿大。随后的肝脏活检显示出通常在Q热中可见的纤维环肉芽肿。该患者后来经血清学诊断为急性Q热，因为伯氏考克斯氏体IgM和IgG滴度分别为64:1和16:1。给予强力霉素治疗后，他完全康复。这表明F-18 FDG PET/CT可能有助于识别作为不明原因发热病因的Q热中的肝脏受累情况。
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