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[淋巴细胞性脑膜神经根炎(班沃思综合征)。莱姆病的神经系统受累]

[Lymphocytic meningoradiculitis (Bannwarth's syndrome). Neurologic involvement of Lyme disease].

作者信息

Maraví Petri E, Oteo Revuelta J A, Pérez Gómez J M, De Miguel Medina C, López Unzu A

机构信息

Sección de Neurología, Hospital Virgen del Camino, Pamplona.

出版信息

Rev Med Univ Navarra. 1989 Jan-Mar;33(1):19-22.

PMID:2490177
Abstract

We describe a patient with Lyme's disease who showed neurologic symptoms of meningoradiculitis (Bannwarth's syndrome) and had no previous history of exposure to tick bite or chronic erythema migrans. He had longterm fever and bilateral facial paralysis. Antibody titres for Borrelia Burgdorferi in serum and cerebrospinal fluid (CSF) were increased. The CSF changes showed an intrathecal production of immunoglobulins (presence of plasmatic cells and immunoblasts; IgG-CSF: IgG-serum ratio much higher than albumin-CSF: Albumin serum ratio, according to Reiber's diagram; presence of oligoclonal bands). Therapeutic response to high doses of penicillin was resolutive. The second day of treatment the patient developed uveitis, that was treated with corticoids.

摘要

我们描述了一名莱姆病患者,该患者表现出脑膜神经根炎(班沃思综合征)的神经系统症状,且既往无蜱叮咬或慢性游走性红斑病史。他长期发热并伴有双侧面部麻痹。血清和脑脊液(CSF)中伯氏疏螺旋体的抗体滴度升高。脑脊液变化显示鞘内免疫球蛋白产生(存在浆细胞和免疫母细胞;根据赖伯图,IgG-CSF:IgG-血清比值远高于白蛋白-CSF:白蛋白血清比值;存在寡克隆带)。高剂量青霉素治疗反应良好。治疗第二天患者出现葡萄膜炎,采用皮质类固醇进行治疗。

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